Results 11 to 20 of about 72,878,926 (153)

Silent spread of mcr-9 in ESBL-producing Enterobacteriaceae clinical isolates, Jimma, Ethiopia. [PDF]

PLoS ONE
BackgroundMobile colistin resistance (MCR) genes, have been increasingly identified worldwide, but their presence and characteristics in Africa remain poorly understood.
Tsegaye Sewunet, Mohammad Razavi, Chaitanya Tellapragada, Christian G Giske   +3 more
doaj   +4 more sources

Genomic analysis of carbapenem- and colistin-resistant Klebsiella pneumoniae complex harbouring mcr-8 and mcr-9 from individuals in Thailand [PDF]

Scientific Reports
The surge in mobile colistin-resistant genes (mcr) has become an increasing public health concern, especially in carbapenem-resistant Enterobacterales (CRE).
Rujirat Hatrongjit, Thidathip Wongsurawat, Piroon Jenjaroenpun, Peechanika Chopjitt, Parichart Boueroy, Yukihiro Akeda, Kazuhisa Okada, Tetsuya Iida, Shigeyuki Hamada, Anusak Kerdsin   +9 more
doaj   +3 more sources

Dissemination dynamics of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones [PDF]

Communications Medicine
Background The polymyxin antibiotic colistin is used as a final line of treatment for life threatening infections caused by multidrug resistant and carbapenem-resistant Gram-negative bacteria.
Odion O. Ikhimiukor, Manuela Montoya-Giraldo, Stephanie S. R. Souza, Ifeoluwa J. Akintayo, Nicole I. Zac Soligno, Maitiú Marmion, Elissa M. Eckhardt, Nisalda Carreiro, Adrienne A. Workman, Isabella W. Martin, Cheryl P. Andam   +10 more
doaj   +4 more sources

Chromosomal coharboring of bla IMP-60 and mcr-9 in Enterobacter asburiae isolated from a Japanese woman with empyema: a case report [PDF]

BMC Infectious Diseases, 2022
Background Polymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as ...
Yusuke Miyazato, Noriko Iwamoto, Masaru Usui, Toyotaka Sato, Tohru Miyoshi-Akiyama, Maki Nagashima, Kazuhisa Mezaki, Kayoko Hayakawa, Norio Ohmagari   +8 more
doaj   +4 more sources

Introduction of the transmissible mobile colistin resistance genes mcr-3 and mcr-9 to the USA via imported seafood [PDF]

mSphere
The emergence and global dissemination of the mobile colistin resistance genes (mcr) threaten the efficacy of colistin, a high-priority, critically important antibiotic that is used to treat complicated infections with multidrug-resistant Gram-negative ...
Jouman W. Hassan, Tongzhou Xu, Marwan Osman, Steven J. Schiff, David Mann, Xiangyu Deng, Jeffrey T. LeJeune, Issmat I. Kassem   +7 more
doaj   +4 more sources

Potential spread of mcr-9-carrying IncHI2 plasmids in Enterobacter hormaechei in Vietnam

Journal of Global Antimicrobial Resistance, 2021
: Objectives: Mobile colistin resistance (mcr) genes are widely distributed around the world. To date, ten major variants of mcr genes are known (mcr-1 to mcr-10).
Van Thi Thu Ha, Linh Dieu Tran, Nguyen Thi Tuyet Mai, Aki Hirabayashi, Son Thai Nguyen, Hoang Huy Tran, Keigo Shibayama, Masato Suzuki   +7 more
doaj   +3 more sources

mcr-9, an Inducible Gene Encoding an Acquired Phosphoethanolamine Transferase in Escherichia coli, and Its Origin. [PDF]

Antimicrob Agents Chemother, 2019
The plasmid-located mcr-9 gene, encoding a putative phosphoethanolamine transferase, was identified in a colistin-resistant human fecal Escherichia coli strain belonging to a very rare phylogroup, the D-ST69-O15:H6 clone. This MCR-9 protein shares 33%
Kieffer N, Royer G, Decousser JW, Bourrel AS, Palmieri M, Ortiz De La Rosa JM, Jacquier H, Denamur E, Nordmann P, Poirel L.   +9 more
europepmc   +9 more sources

One Health Analysis of mcr-Carrying Plasmids and Emergence of mcr-10.1 in Three Species of Klebsiella Recovered from Humans in China

Microbiology Spectrum, 2022
The global dissemination of the mobile colistin resistance (mcr) gene illustrates how the use of colistin in veterinary medicine can affect human health, exemplifying the concept of One Health.
Melissa Chunjiao Liu, Zijuan Jian, Wenen Liu, Junhua Li, Na Pei   +4 more
doaj   +2 more sources

Molecular antibiotic resistance mechanisms and co-transmission of the mcr-9 and metallo-β-lactamase genes in carbapenem-resistant Enterobacter cloacae complex [PDF]

Frontiers in Microbiology, 2022
Carbapenem-resistant Enterobacter cloacae complex (CRECC) has increasingly emerged as a major cause of healthcare-associated infections, with colistin being one of the last-resort antibiotics of treatment.
Shan Jiang, Shan Jiang, Xiaoyu Wang, Xiaoyu Wang, Haidong Yu, Jisheng Zhang, Jianmin Wang, Jie Li, Xinhui Li, Kewang Hu, Kewang Hu, Xue Gong, Xuemei Gou, Yang Yang, Chunjiang Li, Xiaoli Zhang   +15 more
doaj   +2 more sources

Identification of Novel Mobile Colistin Resistance Gene Mcr-10

Emerging Microbes and Infections, 2020
Mobile colistin resistance (mcr) genes represent an emerging challenge. Here we describe a novel mcr gene, mcr-10, on an IncFIA plasmid of an Enterobacter roggenkampii clinical strain.
Yu Feng, Yu Feng, Mei Kang
exaly   +3 more sources