Results 11 to 20 of about 25,588 (94)

Dissemination dynamics of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones [PDF]

Communications Medicine
Background The polymyxin antibiotic colistin is used as a final line of treatment for life threatening infections caused by multidrug resistant and carbapenem-resistant Gram-negative bacteria.
Odion O. Ikhimiukor, Manuela Montoya-Giraldo, Stephanie S. R. Souza, Ifeoluwa J. Akintayo, Nicole I. Zac Soligno, Maitiú Marmion, Elissa M. Eckhardt, Nisalda Carreiro, Adrienne A. Workman, Isabella W. Martin, Cheryl P. Andam   +10 more
doaj   +2 more sources

Chromosomal coharboring of bla IMP-60 and mcr-9 in Enterobacter asburiae isolated from a Japanese woman with empyema: a case report [PDF]

BMC Infectious Diseases, 2022
Background Polymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as ...
Yusuke Miyazato, Noriko Iwamoto, Masaru Usui, Toyotaka Sato, Tohru Miyoshi-Akiyama, Maki Nagashima, Kazuhisa Mezaki, Kayoko Hayakawa, Norio Ohmagari   +8 more
doaj   +2 more sources

First Detection of mcr-9 in a Multidrug-Resistant Escherichia coli of Animal Origin in Italy Is Not Related to Colistin Usage on a Pig Farm [PDF]

Antibiotics, 2023
The emergence of colistin resistance raises growing concerns because of its use as a last-resort antimicrobial for the treatment of severe gram-negative bacterial infections in humans. Plasmid-borne mobile colistin resistance genes (mcr) are particularly
Flavia Guarneri, Cristina Bertasio, Claudia Romeo, Nicoletta Formenti, Federico Scali, Giovanni Parisio, Sabrina Canziani, Chiara Boifava, Federica Guadagno, Maria Beatrice Boniotti, Giovanni Loris Alborali   +10 more
doaj   +2 more sources

Silent spread of mcr-9 in ESBL-producing Enterobacteriaceae clinical isolates, Jimma, Ethiopia. [PDF]

PLoS ONE
BackgroundMobile colistin resistance (MCR) genes, have been increasingly identified worldwide, but their presence and characteristics in Africa remain poorly understood.
Tsegaye Sewunet, Mohammad Razavi, Chaitanya Tellapragada, Christian G Giske   +3 more
doaj   +2 more sources

Emergence of concurrently transmissible mcr-9 and carbapenemase genes in bloodborne colistin-resistant Enterobacter cloacae complex isolated from ICU patients in Kolkata, India [PDF]

Microbiology Spectrum
Colistin resistance in carbapenem-resistant Enterobacter cloacae complex (CR-ECC) infections has grown expeditiously but detecting the underlying mechanism of resistance is often challenging in clinical settings. This study, first of its kind from India,
Gourab Halder, Bhaskar Narayan Chaudhury, Priyanka Denny, Mandira Chakraborty, Subhranshu Mandal, Shanta Dutta   +5 more
doaj   +2 more sources

Genomic analysis of carbapenem- and colistin-resistant Klebsiella pneumoniae complex harbouring mcr-8 and mcr-9 from individuals in Thailand [PDF]

Scientific Reports
The surge in mobile colistin-resistant genes (mcr) has become an increasing public health concern, especially in carbapenem-resistant Enterobacterales (CRE).
Rujirat Hatrongjit, Thidathip Wongsurawat, Piroon Jenjaroenpun, Peechanika Chopjitt, Parichart Boueroy, Yukihiro Akeda, Kazuhisa Okada, Tetsuya Iida, Shigeyuki Hamada, Anusak Kerdsin   +9 more
doaj   +2 more sources

Introduction of the transmissible mobile colistin resistance genes mcr-3 and mcr-9 to the USA via imported seafood [PDF]

mSphere
The emergence and global dissemination of the mobile colistin resistance genes (mcr) threaten the efficacy of colistin, a high-priority, critically important antibiotic that is used to treat complicated infections with multidrug-resistant Gram-negative ...
Jouman W. Hassan, Tongzhou Xu, Marwan Osman, Steven J. Schiff, David Mann, Xiangyu Deng, Jeffrey T. LeJeune, Issmat I. Kassem   +7 more
doaj   +2 more sources

Screening for mobile colistin resistance gene-9 (mcr-9) in multidrug resistant uropathogenic Escherichia coli isolated from patients with urinary tract infections [PDF]

BMC Research Notes
Objective Colistin and Polymyxin B form the reserve group of antibiotics. Resistance to colistin has been increasing across the world including India, posing treatment challenges to clinicians.
Divya Lakshmanan, K. Vanathy, Catherine Thamayandhi, Sreejith Sreekumaran, E. K. Radhakrishnan, S. Srirangaraj   +5 more
doaj   +2 more sources

Emergence of carbapenem-resistant and colistin-susceptible Enterobacter cloacae complex co-harboring bla IMP-1 and mcr-9 in Japan [PDF]

BMC Infectious Diseases, 2020
Background The spread of Enterobacteriaceae producing both carbapenemases and Mcr, encoded by plasmid-mediated colistin resistance genes, has become a serious public health problem worldwide.
Pegah Kananizadeh, Satoshi Oshiro, Shin Watanabe, Shu Iwata, Kyoko Kuwahara-Arai, Masahiro Shimojima, Miho Ogawa, Tatsuya Tada, Teruo Kirikae   +8 more
doaj   +2 more sources

Detection of Five mcr-9-Carrying Enterobacterales Isolates in Four Czech Hospitals [PDF]

mSphere, 2020
The aim of this study was to report the characterization of the first mcr-positive Enterobacterales isolated from Czech hospitals. In 2019, one Citrobacter freundii and four Enterobacter isolates were recovered from Czech hospitals.
Ibrahim Bitar, Costas C. Papagiannitsis, Lucie Kraftova, Katerina Chudejova, Vittoria Mattioni Marchetti, Jaroslav Hrabak   +5 more
doaj   +2 more sources