Results 41 to 50 of about 5,841,978 (243)

The mcr-9 Gene of Salmonella and Escherichia coli Is Not Associated with Colistin Resistance in the United States. [PDF]

Antimicrob Agents Chemother, 2020
Reports of transmissible colistin resistance show the importance of comprehensive colistin resistance surveillance. Recently, a new allele of the mobile colistin resistance ( mcr ) gene family designated mcr-9 , which shows variation in genetic context and colistin susceptibility, was ...
Tyson GH, Li C, Hsu CH, Ayers S, Borenstein S, Mukherjee S, Tran TT, McDermott PF, Zhao S.   +8 more
europepmc   +6 more sources

Emergence of IncHI2 Plasmids With Mobilized Colistin Resistance (mcr)-9 Gene in ESBL-Producing, Multidrug-Resistant Salmonella Typhimurium and Its Monophasic Variant ST34 From Food-Producing Animals in Italy

Frontiers in Microbiology, 2021
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant isolated in 2014–2019 from Italian poultry/livestock (n = 165) and foodstuff (n = 12), previously screened for antimicrobial susceptibility and assigned to ST34 and single ...
Elena Lavinia Diaconu, Patricia Alba, Fabiola Feltrin, Paola Di Matteo, Manuela Iurescia, Eleonora Chelli, Valentina Donati, Ilaria Marani, Angelo Giacomi, Alessia Franco, Virginia Carfora   +10 more
doaj   +1 more source

Genetic Characterization of Enterobacter hormaechei Co-Harboring bla _NDM-1 and mcr-9 Causing Upper Respiratory Tract Infection. [PDF]

Infect Drug Resist, 2022
With the spread of multiple drug-resistant bacteria, bla NDM-1 and mcr-9 have been detected in various bacteria worldwide. However, the simultaneous detection of bla NDM-1 and mcr-9 in Enterobacter hormaechei has been rarely reported. This study identified an E. hormaechei strain carrying both bla NDM-1 and mcr-9.
Liu H, Wang D, Tang M, Jia P, Huo Y, Wei E, Xu H, Chi X, Wang H.   +8 more
europepmc   +5 more sources

Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

Journal of Antimicrobial Chemotherapy, 2020
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling, Wenjuan, Yin, Zhangqi, Shen, Yang, Wang, Jianzhong, Shen, Timothy R, Walsh   +5 more
openaire   +2 more sources

Plasmid maps of pACYC-Para-MCR-1 and pACYC-NP-MCR-1.

, 2023
The plasmid for expressing MCR-1 or M6 under the regulation of arabinose promoter was shown as (A), and the one for expressing target proteins under the regulation of MCR-1 native promoter was shown as (B).
Chenchen Zhang (324804), Siyuan Feng (5998040), Yaxin Li (312731), Lingxuan Lyu (17628265), Yohei Doi (188766), Wanfei Liang (8610954), Fang Bai (1612534), Lin Wang (11986), Lan-Lan Zhong (9702537), Dianrong Zhou (11816537), Jiachen Li (669381), Hui Zhao (7395), Yong Chen (109188), Nicole Stoesser (220513), Guo-Bao Tian (3365051), Lujie Liang (8610960), Wenjing Wei (525144)   +16 more
core   +1 more source

mcr-1 regulatory variants

, 2023
Associated paper:    Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance  Lois Ogunlana, Liam P. Shaw, Divjot Kaur, Pramod Jangir, Timothy Walsh, Stephan Uphoff, and R.C. MacLean.  Preprint version: https://doi.org/10.
Liam Shaw (5487083)
core   +1 more source

Detection and genomic characterization of mcr-9 in Enterobacter hormaechei recovered from a pediatric patient in Lebanon

Infection, Genetics and Evolution, 2021
The emergence and spread of mobilized colistin resistance (mcr) genes are a global health concern.In this study, we report the detection and genomic characterization of mcr-9 in a colistin-susceptible Enterobacter hormaechei (EH23) recovered from a pediatric patient in Lebanon.EH23 was susceptible to colistin with a minimal inhibitory concentration ...
Ragheed, Khodor, Tamara, Salloum, Tamima, El Jisr, Mira, El Chaar, Sima, Tokajian   +4 more
openaire   +2 more sources

DataSheet_1_Emergence of Neonatal Sepsis Caused by MCR-9- and NDM-1-Co-Producing Enterobacter hormaechei in China.pdf

, 2022
Mobile colistin resistance (mcr) genes represent an emerging threat to public health. Reports on the prevalence, antimicrobial profiles, and clonality of MCR-9-producing Enterobacter cloacae complex (ECC) isolates on a national scale in China are limited.
Xinjun Hu (412383), Beiwen Zheng (221103), Ruishan Liu (7845356), Jianfeng Han (589925), Hao Xu (6530), Chunlei Chen (352543), Lingjiao Wu (729757), Hao Fu (755255), Yonghong Xiao (248558)   +8 more
core   +1 more source

Molecular characterization of NDM-1-producing carbapenem-resistant E. cloacae complex from a tertiary hospital in Chongqing, China

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundThe aim of this study was to clarify the molecular characterization of NDM-1-producing carbapenem-resistant Enterobacter cloacae complex (CREL) at a teaching hospital in Chongqing, China.MethodsAntimicrobial susceptibility and resistance genes ...
Kewang Hu, Kewang Hu, Jisheng Zhang, Jingbo Zou, Lingyi Zeng, Lingyi Zeng, Jie Li, Jianmin Wang, Wenzhang Long, Xiaoli Zhang   +9 more
doaj   +1 more source

First reported detection of the mobile colistin resistance genes, mcr-8 and mcr-9, in the Irish environment [PDF]

, 2023
The emergence and dissemination of mobile colistin resistance (mcr) genes across the globe poses a significant threat to public health, as colistin remains one of the last line treatment options for multi-drug resistant infections. Environmental samples (
Morris, Dearbháile, Niall Delappe, Delappe, Niall, Brigid Hooban, Cahill, Niamh, Dearbháile Morris, Liam Burke, Cormican, Martin, O'Connor, Louise, Chueiri, Alexandra, Montserrat Gutierrez, Hooban, Brigid, Francesca McDonagh, Catherine Burgess, Burke, Liam, Louise O'Connor, Maeve Louise Farrell, Burgess, Catherine, Wendy Brennan, McDonagh, Francesca, Prendergast, Deirdre, Georgios Miliotis, Kelly Fitzhenry, Joyce, Aoife, Miliotis, Georgios, Farrell, Maeve Louise, Deirdre Prendergast, Martin Cormican, Alexandra Chueiri, Fitzhenry, Kelly, Brennan, Wendy, Aoife Joyce, Niamh Cahill, Bray, James, Gutierrez, Montserrat, James E. Bray   +35 more
core   +1 more source