Results 61 to 70 of about 5,841,978 (243)

Potential sources and characteristic occurrence of mobile colistin resistance (mcr) gene-harbouring bacteria recovered from the poultry sector: a literature synthesis specific to high-income countries [PDF]

PeerJ, 2021
Understanding the sources, prevalence, phenotypic and genotypic characteristics of mcr gene-harbouring bacteria (MGHB) in the poultry sector is crucial to supplement existing information.
Madubuike Umunna Anyanwu, Ishmael Festus Jaja, Charles Odilichukwu R. Okpala, Chinwe-Juliana Iwu Jaja, James Wabwire Oguttu, Kennedy Foinkfu Chah, Vincent Shodeinde Shoyinka   +6 more
doaj   +2 more sources

Coproduction Of MCR-9 And NDM-1 By Colistin-Resistant Enterobacter hormaechei Isolated From Bloodstream Infection. [PDF]

Infect Drug Resist, 2019
Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern.In this study, we reported the first clinical colistin and carbapenem-resistant Enterobacter ...
Yuan Y, Li Y, Wang G, Li C, Xiang L, She J, Yang Y, Zhong F, Zhang L.   +8 more
europepmc   +5 more sources

High prevalence of colistin resistance and mcr-9/10 genes in Enterobacter spp. in a tertiary hospital over a decade

International Journal of Antimicrobial Agents, 2022
Enterobacter spp. are members of the 'ESKAPE' group of pathogens, which which are recognised as the leading cause of multidrug-resistant (MDR) hospital-acquired infections. Colistin is usually regarded as a last-line therapeutic option for MDR Gram-negative bacilli infections. However, colistin-resistant Enterobacter spp.
Weichao Liao, Yushan Cui, Jingjing Quan, Dongdong Zhao, Xinhong Han, Qiucheng Shi, Qian Wang, Yan Jiang, Xiaoxing Du, Xi Li, Yunsong Yu   +10 more
openaire   +2 more sources

Large-scale genomic survey and characterization of mcr genes carried by foodborne Cronobacter isolates

mSystems, 2023
Antibiotic resistance has become a worldwide public health and biosafety problem. The clinical efficacy of colistin was jeopardized by the report of the first mobile colistin resistance (mcr) gene, and subsequently, the mcr-gene family of mcr-1 to mcr-10
Qianhui Zhu, Jinrui Hu, Na Liu, Heyuan Qi, Xiaoli Du, Zhigang Cui, Yan Sun, Yadong Liu, Songnian Hu, Linhuan Wu, Haijian Zhou, Zilong He, Juncai Ma   +12 more
doaj   +1 more source

Klebsiella pneumoniae Complex Harboring mcr-1, mcr-7, and mcr-8 Isolates from Slaughtered Pigs in Thailand

, 2021
Dissemination of the mobile colistin resistance gene mcr in Enterobacterales among humans, animals, and the environment is a public health issue. We characterized mcr genes in the Klebsiella pneumoniae complex (KpnC) isolated from slaughtered pigs in ...
Anusak Kerdsin, Parichart Boueroy, Nattamol Phetburom, Yukihiro Akeda, Peechanika Chopjitt, Rujirat Hatrongjit, Shigeyuki Hamada, Suphachai Nuanualsuwan   +7 more
core   +1 more source

Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic

Frontiers in Microbiology, 2023
The occurrence of colistin resistance has increased rapidly among Enterobacterales around the world. We performed a national survey of plasmid-mediated colistin resistance in human clinical isolates through a retrospective analysis of samples from 2009 ...
Marketa Zelendova, Marketa Zelendova, Costas C. Papagiannitsis, Petra Sismova, Petra Sismova, Matej Medvecky, Matej Medvecky, Katarina Pomorska, Jana Palkovicova, Jana Palkovicova, Kristina Nesporova, Vladislav Jakubu, Vladislav Jakubu, Ivana Jamborova, Helena Zemlickova, Helena Zemlickova, Monika Dolejska, Monika Dolejska, Monika Dolejska, Monika Dolejska, Working Group for Monitoring of Antibiotic Resistance   +20 more
doaj   +1 more source

Co-occurrence of blaNDM–1 and mcr-9 in a Conjugative IncHI2/HI2A Plasmid From a Bloodstream Infection-Causing Carbapenem-Resistant Klebsiella pneumoniae

Frontiers in Microbiology, 2021
Spread of the carbapenemase-encoding and mobilized colistin resistance (mcr) genes among Enterobacteriales poses a great threat to global public health, especially when the both genes are transferred by a single plasmid.
Zhou Liu, Xiubing Hang, Xiao Xiao, Wenwen Chu, Xin Li, Yangyang Liu, Yangyang Liu, Yangyang Liu, Xi Li, Qiang Zhou, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +13 more
doaj   +1 more source

First reported genome of an mcr-9-mediated colistin-resistant Salmonella Typhimurium isolate from Brazilian livestock

Journal of Global Antimicrobial Resistance, 2020
To investigate the genetic context of colistin resistance in anmcr-9-harbouring Salmonella Typhimurium ST19 strain from swine in Brazil.Minimum inhibitory concentrations (MIC) to colistin were determined by broth microdilution. Whole-genome sequencing was performed on an Illumina MiSeq system, followed by de novo genome assembly using SPAdes 1.13.1 ...
Elma L. Leite, Wydemberg J. Araújo, Tatiana R. Vieira, Karoline S. Zenato, Priscylla C. Vasconcelos, Samuel Cibulski, Patricia E.N. Givisiez, Marisa R.I. Cardoso, Celso J.B. Oliveira   +8 more
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Additive Manufacturing of Alumina‐Reinforced Elastomers

Advanced Engineering Materials, EarlyView.
Vat‐photopolymerized elastomers reinforced with platelet‐shaped alumina exhibited preferential orientation, reduced porosity, and significantly enhanced mechanical performance. A 3 wt% platelet loading increased tensile strength from 12.4 to 45.7 MPa, highlighting the critical role of filler morphology in elastomeric VPP composites.
Majid Barzegar Keyvani, Zongwen Fu, Robert Göstl, Hamed Shokri, Carmine Putignano, Gianluca Percoco, Bilal Gökce   +6 more
wiley   +1 more source