Results 61 to 70 of about 72,878,926 (153)

mcr-1 regulatory variants

, 2023
Associated paper:    Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance  Lois Ogunlana, Liam P. Shaw, Divjot Kaur, Pramod Jangir, Timothy Walsh, Stephan Uphoff, and R.C. MacLean.  Preprint version: https://doi.org/10.
Liam Shaw (5487083)
core   +1 more source

Table_3_Development of a Novel mcr-6 to mcr-9 Multiplex PCR and Assessment of mcr-1 to mcr-9 Occurrence in Colistin-Resistant Salmonella enterica Isolates From Environment, Feed, Animals and Food (2011–2018) in Germany.docx

, 2020
The polymyxin antibiotic colistin has been used in decades for treatment and prevention of infectious diseases in livestock. Nowadays, it is even considered as last-line treatment option for severe human infections caused by multidrug- and carbapenem ...
Katharina Thomas (2889137), Beatrice Baumann (8395545), Burkhard Malorny (93357), Jens Andre Hammerl (6584027), Istvan Szabo (4631782), Jennie Fischer (599845), Carlus Deneke (169004), Maria Borowiak (3185991)   +7 more
core   +1 more source

Occurrence of mcr-1 and mcr-2 colistin resistance genes in porcine Escherichia coli isolates (2010–2020) and genomic characterization of mcr-2-positive E. coli [PDF]

, 2022
IntroductionThe global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria.
Torsten Semmler, Katharina Kerner, Göpel, Lisa, Lisa Göpel, Christa Ewers, Kerner, Katharina, Ellen Prenger-Berninghoff, Ewers, Christa, Semmler, Torsten, Bauerfeind, Rolf, Prenger-Berninghoff, Ellen, Rolf Bauerfeind   +11 more
core   +1 more source

A link between the newly described colistin resistance gene mcr-9 and clinical Enterobacteriaceae isolates carrying blaSHV-12 from horses in Sweden

Journal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to investigate the occurrence of the newly described transferable colistin resistance gene mcr-9 in extended-spectrum β-lactamase (ESBL)-producing clinical Enterobacteriaceae isolates from horses in Sweden.
Stefan Börjesson, Christina Greko, Mattias Myrenås, Annica Landén, Oskar Nilsson, Karl Pedersen   +5 more
doaj   +1 more source

First Report of Salmonella Serovar Typhimurium and Monophasic Typhimurium Clinical Isolates Harboring mcr-9 in Portugal

Acta Médica Portuguesa, 2023
N/a.
Leonor Silveira, Ângela Pista
openaire   +3 more sources

Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes [PDF]

, 2018
Background and aim: Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 ...
Hammerl, Jens Andre, Sophie A Granier, Cristina De Frutos Escobar, Kjeldgaard, Jette,, Ana Rita Rebelo, Carattoli, Alessandra, Borowiak, Maria, Valeria Bortolaia, Maria Borowiak, Hendriksen, Rene S., Patricia Alba, Hendriksen, Rene,, Hansen, Inge,, Malorny, Burkhard, Granier, Sophie, Surbhi Malhotra-Kumar, Antonio Battisti, De Frutos Escobar, Cristina, Franco, Alessia, Inge M Hansen, Rene S Hendriksen, Hammerl, Jens,, Pedersen, Susanne,, Leekitcharoenphon, Pimlapas, Hansen, Inge M., Rebelo, Ana Rita, de Frutos, Cristina, Jette S Kjeldgaard, Alessia Franco, Pedersen, Susanne K., Karlsmose Pedersen, Susanne, Malhotra-Kumar, Surbhi, Kjeldgaard, Jette S., Pimlapas Leekitcharoenphon, Alba, Patricia, Burkhard Malorny, Rebelo, Ana-Rita, Alessandra Carattoli, Granier, Sophie A., Beatriz Guerra, Perrin-Guyomard, Agnes, Battisti, Antonio, Bortolaia, Valeria, Escobar, Susanne K Pedersen, Agnes Perrin-Guyomard, Guerra, Beatriz, Laura Villa, Jens Andre Hammerl, Villa, Laura, Pedersen, Susanne, K., Carattoli A, Hendriksen, Rene, S, Leekitcharoenphon P, Hendriksen RS, Hammerl JA, Malorny B, Borowiak M, Battisti A, Rebelo AR, Guerra B, Escobar and Malhotra-Kumar S, Bortolaia V, Granier SA, Kjeldgaard, Jette, S., Hansen IM, de Frutos C, Perrin-Guyomard A, Alba P, Pedersen SK, Villa L, Hammerl, Jens, Andre, Hansen, Inge, M, Kjeldgaard JS, Franco A   +74 more
core   +3 more sources

Frequent convergence of mcr-9 and carbapenemase genes in Enterobacter cloacae complex driven by epidemic plasmids and host incompatibility

, 2022
Convergence of mcr and carbapenemase genes has been sporadically detected in Enterobacter cloacae complex (ECC) with an upward trend. However, the state of the epidemic and underlying mechanism of such convergence has been poorly understood.
Kai Zhou (125548), Tingting Xu (307597), Yuxin Chen (126718), Qiuhui Huang (13109055), Dandan Chen (394689), Yuemei Lu (792212), Weiyuan Wu (792211), Junxi Huang (13109052), Chun-Xu Xue (9998759)   +8 more
core   +1 more source

Co-occurrence of blaNDM-1, rmtC, and mcr-9 in multidrug-resistant Enterobacter kobei strain isolated from an infant with urinary tract infection

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The co-emergence of mcr and carbapenem resistance genes in Gram-negative bacteria is a serious problem. This study aims to clarify the genetic characteristic of one novel multidrug-resistant Enterobacter kobei EC1382 with mcr-9 causing ...
Haiyan Zeng, Yujing Tan, Jianhui Su, Fei Gao, Tao Lei, Bingshao Liang   +5 more
doaj   +1 more source

Large-scale genomic survey and characterization of mcr genes carried by foodborne Cronobacter isolates

mSystems, 2023
Antibiotic resistance has become a worldwide public health and biosafety problem. The clinical efficacy of colistin was jeopardized by the report of the first mobile colistin resistance (mcr) gene, and subsequently, the mcr-gene family of mcr-1 to mcr-10
Qianhui Zhu, Jinrui Hu, Na Liu, Heyuan Qi, Xiaoli Du, Zhigang Cui, Yan Sun, Yadong Liu, Songnian Hu, Linhuan Wu, Haijian Zhou, Zilong He, Juncai Ma   +12 more
doaj   +1 more source

High prevalence of colistin resistance and mcr-9/10 genes in Enterobacter spp. in a tertiary hospital over a decade

International Journal of Antimicrobial Agents, 2022
Enterobacter spp. are members of the 'ESKAPE' group of pathogens, which which are recognised as the leading cause of multidrug-resistant (MDR) hospital-acquired infections. Colistin is usually regarded as a last-line therapeutic option for MDR Gram-negative bacilli infections. However, colistin-resistant Enterobacter spp.
Weichao Liao, Yushan Cui, Jingjing Quan, Dongdong Zhao, Xinhong Han, Qiucheng Shi, Qian Wang, Yan Jiang, Xiaoxing Du, Xi Li, Yunsong Yu   +10 more
openaire   +2 more sources