Results 121 to 130 of about 1,695,806 (215)

Decoding the origins, spread, and global risks of mcr-9 gene

open access: yeseBioMedicine
The global spread of the plasmid-mediated mcr (mobilized colistin resistance) gene family presents a significant threat to the efficacy of colistin, a last-line defense against numerous Gram-negative pathogens. The mcr-9 is the second most prevalent variant after mcr-1.A dataset of 698 mcr-9-positive isolates from 44 countries is compiled.
Kaiwen Song   +9 more
openaire   +2 more sources

Virtual brain endocasts of the palaeanodont Metacheiromys marshi and the neurosensory evolution of early Pholidotamorpha

open access: yesJournal of Anatomy, Volume 249, Issue 4, Page 821-846, October 2026.
We describe the endocranial anatomy of Metacheiromys marshi. Decrease in olfaction and eye movement control occurred through time in Pholidotamorpha and is likely linked to fossorial adaptations. The development of the orbital gyrus might be related to the evolution of myrmecophagy and the emergence of a protrusile tongue in early Pholidotamorpha ...
Eduard Cabasés Bru   +4 more
wiley   +1 more source

Transferability of the mcr-1 Colistin Resistance Gene [PDF]

open access: yesMicrobial Drug Resistance, 2017
Dénervaud Tendon, Valérie   +2 more
openaire   +4 more sources

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

open access: yesAdvanced Functional Materials, Volume 36, Issue 73, 10 September 2026.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik   +8 more
wiley   +1 more source

A Fully Defined GelMA‐Based Matrix Allows Fine Tuning of Tissue‐Relevant Biomechanical and Biochemical Cues for Organoid Culture

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 33, 4 September 2026.
A fully defined GelMA‐based ECM platform integrates tunable tissue‐relevant stiffness with laminin–entactin biochemical supplementation to support mouse small intestinal organoid growth. Coordinated control of mechanical and biochemical cues promotes robust proliferation, budding morphogenesis, differentiation, and passaging, providing a reproducible ...
Junyi Liu   +3 more
wiley   +1 more source

Trends of the environmental spread of mcr genes in Latin America

open access: yesThe Lancet Microbe, 2023
João Pedro Rueda, Furlan   +2 more
openaire   +2 more sources

Plasma Gelation as an Overlooked Determinant of Transfection Efficiency in Protein Corona‐Coated Lipid Nanoparticles: Implications for In Vitro–In Vivo Translation

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi   +14 more
wiley   +1 more source

One Health study of mobile colistin resistance (mcr) in Salmonella enterica in Canada, 2017–2022

open access: yesMicrobiology Spectrum
Colistin is a last-resort treatment for highly drug-resistant bacterial infections. Of 47,184 Salmonella isolates collected from 2017 to 2022 in Canada from human and animal/food sources, mobile colistin resistance (mcr) variants conferring colistin ...
Ketna Mistry   +26 more
doaj   +1 more source

1‐D Collocated Dual‐Gradient Sensory Fibers for Comprehensive Sensing and Decoding of Complex Human Motion and Physiology

open access: yesAdvanced Materials, Volume 38, Issue 53, 21 September 2026.
Coupled materials design enables a monolithic fiber that integrates complementary sensing regimes into a single wearable strand. By preserving informative signal features across subtle physiological deformation, large body motion, and mixed mechanical inputs, the dual‐gradient architecture generates synchronized, less redundant outputs that improve ...
Yunheum Lee   +13 more
wiley   +1 more source

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