Results 131 to 140 of about 1,695,806 (215)

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

A dilemma resolved? Towards a revised philosophy of conservation education [PDF]

, 2002
The guidelines for conservation education agreed by the European Confederation of Conservator-restorers’ Organisations’ state that “The only reasonable way of training in conservation/restoration is full time at university level or at an equivalent level,
Schiro, Joseph, Conference on Scientific Aspects of Conservation, Cannataci, Joseph A., Caruana, Martina, Malta Centre for Restoration (MCR)   +4 more
core  

The risk of pig and chicken farming for carriage and transmission of Escherichia coli containing extended-spectrum beta-lactamase (ESBL) and mobile colistin resistance (mcr) genes in Thailand. [PDF]

Microb Genom, 2023
Sudatip D, Mostacci N, Tiengrim S, Thamlikitkul V, Chasiri K, Kritiyakan A, Phanprasit W, Thinphovong C, Abdallah R, Baron SA, Rolain JM, Morand S, Oppliger A, Hilty M.   +13 more
europepmc   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu, Xiaoyang Wu, Xiaoyin Liu, Yuyan Wang, Shichao Jiang, Kai Wu, Gaowei Li, Jie Ding, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan, Liangxue Zhou   +12 more
wiley   +1 more source

Epidemiology, genetic dynamics, and transmission of the mcr-1 gene in China

Emerging Microbes & Infections
Colistin is a broad-spectrum antibiotic that kills bacteria through the disruption of the cell membrane, making it effective against various bacterial infections. Since the first global report of mobile colistin-resistant (mcr-1)-positive bacteria, which were discovered and described by Chinese scientists in 2015, monitoring and research on these ...
Wang, Boqian, Li, Zhong, Chen, Mingliang, Wang, Yuxin, Aimaiti, Buaijier, Fu, Jingjing, Li, Kexin, Peng, Zhixi, Zhang, Rui, Wang, Tianyi, Wang, Honghao, Gu, Bin, Song, Hongbin, Ren, Hongguang, Hu, Xiaofeng   +14 more
openaire   +3 more sources

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, Volume 13, Issue 53, 24 September 2026.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Dissemination dynamics of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones

Communications Medicine
The polymyxin antibiotic colistin is used as a final line of treatment for life threatening infections caused by multidrug resistant and carbapenem-resistant Gram-negative bacteria. Mobile colistin resistance genes mcr-9 and mcr-10 are increasingly detected in Enterobacteriaceae but their epidemiology is poorly understood.The genetic characteristics of
Odion O. Ikhimiukor, Manuela Montoya-Giraldo, Stephanie S. R. Souza, Ifeoluwa J. Akintayo, Nicole I. Zac Soligno, Maitiú Marmion, Elissa M. Eckhardt, Nisalda Carreiro, Adrienne A. Workman, Isabella W. Martin, Cheryl P. Andam   +10 more
openaire   +2 more sources

Aeromonas and mcr–3: A Critical Juncture for Transferable Polymyxin Resistance in Gram-Negative Bacteria

Pathogens
Polymyxin antibiotics B and colistin are considered drugs of last resort for the treatment of multi-drug and carbapenem-resistant Gram-negative bacteria.
Nathan L. McDonald, David W. Wareham, David C. Bean   +2 more
doaj   +1 more source

Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface. [PDF]

Gut Pathog, 2020
Javed H, Saleem S, Zafar A, Ghafoor A, Shahzad AB, Ejaz H, Junaid K, Jahan S.   +7 more
europepmc   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source