Results 131 to 140 of about 1,822,998 (209)

Epidemiology, genetic dynamics, and transmission of the mcr-1 gene in China

Emerging Microbes & Infections
Colistin is a broad-spectrum antibiotic that kills bacteria through the disruption of the cell membrane, making it effective against various bacterial infections. Since the first global report of mobile colistin-resistant (mcr-1)-positive bacteria, which were discovered and described by Chinese scientists in 2015, monitoring and research on these ...
Wang, Boqian, Li, Zhong, Chen, Mingliang, Wang, Yuxin, Aimaiti, Buaijier, Fu, Jingjing, Li, Kexin, Peng, Zhixi, Zhang, Rui, Wang, Tianyi, Wang, Honghao, Gu, Bin, Song, Hongbin, Ren, Hongguang, Hu, Xiaofeng   +14 more
openaire   +3 more sources

The first report of emerging mobilized colistin-resistance (mcr) genes and ERIC-PCR typing in Escherichia coli and Klebsiella pneumoniae clinical isolates in southwest Iran

, 2019
Mojtaba Moosavian,1,2 Nasrin Emam21Infectious and Tropical Diseases Research Center, Health Research Institue, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 2Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of
Moosavian M, Emam N
core  

Dissemination dynamics of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones

Communications Medicine
The polymyxin antibiotic colistin is used as a final line of treatment for life threatening infections caused by multidrug resistant and carbapenem-resistant Gram-negative bacteria. Mobile colistin resistance genes mcr-9 and mcr-10 are increasingly detected in Enterobacteriaceae but their epidemiology is poorly understood.The genetic characteristics of
Odion O. Ikhimiukor, Manuela Montoya-Giraldo, Stephanie S. R. Souza, Ifeoluwa J. Akintayo, Nicole I. Zac Soligno, Maitiú Marmion, Elissa M. Eckhardt, Nisalda Carreiro, Adrienne A. Workman, Isabella W. Martin, Cheryl P. Andam   +10 more
openaire   +2 more sources

Aeromonas and mcr–3: A Critical Juncture for Transferable Polymyxin Resistance in Gram-Negative Bacteria

Pathogens
Polymyxin antibiotics B and colistin are considered drugs of last resort for the treatment of multi-drug and carbapenem-resistant Gram-negative bacteria.
Nathan L. McDonald, David W. Wareham, David C. Bean   +2 more
doaj   +1 more source

Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface. [PDF]

Gut Pathog, 2020
Javed H, Saleem S, Zafar A, Ghafoor A, Shahzad AB, Ejaz H, Junaid K, Jahan S.   +7 more
europepmc   +1 more source

The risk of pig and chicken farming for carriage and transmission of Escherichia coli containing extended-spectrum beta-lactamase (ESBL) and mobile colistin resistance (mcr) genes in Thailand. [PDF]

Microb Genom, 2023
Sudatip D, Mostacci N, Tiengrim S, Thamlikitkul V, Chasiri K, Kritiyakan A, Phanprasit W, Thinphovong C, Abdallah R, Baron SA, Rolain JM, Morand S, Oppliger A, Hilty M.   +13 more
europepmc   +1 more source

Molecular Detection of the mcr Genes by Multiplex PCR. [PDF]

Infect Drug Resist, 2020
Liu J, Zhang Z, Feng Y, Hu H, Yu Y, Qiu L, Liu H, Guo Z, Huang J, Du C, Qiu J.   +10 more
europepmc   +1 more source

Induction of proteome changes involved in the cloning of mcr-1 and mcr-2 genes in Escherichia coli DH5-α strain to evaluate colistin resistance

: Objectives: Plasmid genes, termed mobile colistin resistance-1 (mcr-1) and mobile colistin resistance-2 (mcr-2), are associated with resistance to colistin in Escherichia coli (E. coli).
Fadhil S. Kamounah, Mohammad Ahangarzadeh Rezaee, Ehsaneh Khodadadi, Khudaverdi Ganbarov, Hossein Samadi Kafil, Reza Ghotaslou, Hadi Feizi, Maryam Alizadeh, Hadi Azimi   +8 more
core   +1 more source

Screening for the presence of mcr-1/mcr-2 genes in Shiga toxin-producing Escherichia coli recovered from a major produce-production region in California.

, 2017
The rapid spreading of polymyxin E (colistin) resistance among bacterial strains through the horizontally transmissible mcr-1 and mcr-2 plasmids has become a serious concern.
Xiaohua He, Beatriz Quiñones, Jaszemyn C Yambao, Daniela Mavrici, Bertram G Lee   +4 more
core   +1 more source

Introduction of the transmissible mobile colistin resistance genes mcr-3 and mcr-9 to the USA via imported seafood

mSphere
The emergence and global dissemination of the mobile colistin resistance genes (mcr) threaten the efficacy of colistin, a high-priority, critically important antibiotic that is used to treat complicated infections with multidrug-resistant Gram-negative ...
Jouman W. Hassan, Tongzhou Xu, Marwan Osman, Steven J. Schiff, David Mann, Xiangyu Deng, Jeffrey T. LeJeune, Issmat I. Kassem   +7 more
doaj   +1 more source