Results 11 to 20 of about 33,185 (190)

Clonal Stabilization Reveals a DAO/3MST-Expressing MDCK Subpopulation With Robust d-Cysteine-Mediated H<sub>2</sub>S Production. [PDF]

open access: yesFASEB J
A subpopulation of MDCK (NBL‐2) cells, an epithelial cell line derived from the normal kidney, expresses DAO and 3MST. The DAO/3MST‐expressing cells are progressively eliminated during passaging; however, clonal isolation enables the establishment of sublines that maintain stable H2S production. Clonal cells co‐expressing DAO and 3MST therefore provide
Miyamoto A   +4 more
europepmc   +2 more sources

Baicalin Exhibits a Protective Effect against Cisplatin-Induced Cytotoxic Damage in Canine Renal Tubular Epithelial Cells

open access: yesMetabolites, 2023
Renal failure is a common chronic disease in dogs that substantially affects both their quality of life and longevity. The objective of this study was to assess the protective mechanisms of baicalin in cisplatin-induced Madin–Darby canine kidney (MDCK ...
Yao Wang   +4 more
doaj   +1 more source

TRAF3 deficiency in MDCK cells improved sensitivity to the influenza A virus

open access: yesHeliyon, 2023
Tumor necrosis factor receptor-associated factor 3 (TRAF3), an adaptor protein, has significant and varying effects on immunity depending on cell types. The role of TRAF3 in Madin-Darby Canine Kidney Epithelial (MDCK) cell resistance to influenza A virus
Yang Le   +14 more
doaj   +1 more source

Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells. [PDF]

open access: yesPLoS ONE, 2016
The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions.
Chia Chu   +3 more
doaj   +1 more source

Alternative Experimental Models for Studying Influenza Proteins, Host–Virus Interactions and Anti-Influenza Drugs

open access: yesPharmaceuticals, 2019
Ninety years after the discovery of the virus causing the influenza disease, this malady remains one of the biggest public health threats to mankind. Currently available drugs and vaccines only partially reduce deaths and hospitalizations.
Sonja C. J. H. Chua   +3 more
doaj   +1 more source

Comparison of different cell substrates on the measurement of human influenza virus neutralizing antibodies. [PDF]

open access: yesPLoS ONE, 2012
Eight cell lines were systematically compared for their permissivity to primary infection, replication, and spread of seven human influenza viruses. Cell lines were of human origin (Caco-2, A549, HEp-2, and NCI-H292), monkey (Vero, LLC-MK2), mink (Mv1 Lu)
Weiguo Zhai   +6 more
doaj   +1 more source

TGM2 inhibits the proliferation, migration and tumorigenesis of MDCK cells.

open access: yesPLoS ONE, 2023
Madin-Darby canine kidney (MDCK) cells are one of the main cell lines used for influenza vaccine production due to their high virus yield and low mutation resistance.
Zhenyu Qiu   +12 more
doaj   +1 more source

Molecular characterization and phylogenetic analysis of a canine parvovirus isolate in India

open access: yesVeterinární Medicína, 2009
Canine parvovirus 2 (CPV-2) is the causative agent of acute hemorrhagic enteritis and myocarditis in dogs. In this study the nucleotide sequence of the VP1/VP2 gene of a CPV isolate from India was analyzed and the phylogenetic relationship with other CPV
S. Nandi, S. Chidri, M. Kumar
doaj   +1 more source

High-Throughput MicroRNA Profiles of Permissive Madin-Darby Canine Kidney Cell Line Infected with Influenza B Viruses

open access: yesViruses, 2019
Victoria and Yamagata lineages of influenza B viruses are globally circulating in seasonal epidemics. Madin−Darby canine kidney (MDCK) cells are permissive for viral isolation and vaccine manufacture. Nevertheless, the interplay between influenza B
Suthat Saengchoowong   +6 more
doaj   +1 more source

Distinct susceptibility and applicability of MDCK derivatives for influenza virus research. [PDF]

open access: yesPLoS ONE, 2017
Madin-Darby Canine Kidney (MDCK) cells are widely utilized as a substrate for influenza virus isolation and propagation due to the high yields of virus.
Shih-Chao Lin   +4 more
doaj   +1 more source

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