Results 31 to 40 of about 41,345 (224)
Regulation of caveolin and caveolae by cholesterol in MDCK cells [PDF]
Journal of Lipid Research, 1998 We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis, or beta-trimethyl cyclodextrin (CD), a cholesterol sequestering drug.
Hailstones, D. +3 more
openaire +6 more sources
Steviol reduces MDCK Cyst formation and growth by inhibiting CFTR channel activity and promoting proteasome-mediated CFTR degradation. [PDF]
PLoS ONE, 2013 Cyst enlargement in polycystic kidney disease (PKD) involves cAMP-activated proliferation of cyst-lining epithelial cells and transepithelial fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR) chloride ...
Chaowalit Yuajit +5 more
doaj +1 more source
Comparison of mutation patterns in full-genome A/H3N2 influenza sequences obtained directly from clinical samples and the same samples after a single MDCK passage. [PDF]
PLoS ONE, 2013 Human influenza viruses can be isolated efficiently from clinical samples using Madin-Darby canine kidney (MDCK) cells. However, this process is known to induce mutations in the virus as it adapts to this non-human cell-line.
Hong Kai Lee +6 more
doaj +1 more source
PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells. [PDF]
PLoS ONE, 2016 The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI).
Alexander Arkhipenko +4 more
doaj +1 more source
Angewandte Chemie, EarlyView.A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Alexander M. Stephens +9 more
wiley +2 more sources
Replication kinetics in MDCK or MDCK-SIAT1 cells.
, 2013 MDCK (panel A) or MDCK-SIAT1 (panel B) cells were inoculated with 0.001 TCID50 virus per cell of recNL/602 (black circles), isolate NL/2631-R223 (black triangles) and recNL/602-I223R (open circles).
Anne Van der Linden (343087) +13 more
core +1 more source
Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies
, 2013 Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Titball, R.W. +21 more
core +1 more source
Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. [PDF]
, 2014 Identifying and characterising potential new therapeutic agents to target cell proliferation may provide improved treatments for neoplastic disorders such as cancer and polycystic ...
Baines, D +20 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Ganglioside GM2 is substrate for a sialidase in MDCK cells
FEBS Letters, 1998 GM1 ganglioside carrying a fluorescent fatty acid in substitution of the natural one, has been administered to cultured Madin‐Darby canine kidney (MDCK) cells for different pulse times (0.5–24 h), and its metabolic fate was followed. The fluorescent GM2, asialo‐GM2, asialo‐GM1 and ceramide were the only detectable metabolites.
MARCHESINI, Sergio +4 more
openaire +2 more sources