Results 51 to 60 of about 60,380 (203)
The F-actin filament capping protein CapG is a bona fide nucleolar protein [PDF]
Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the question how actin dynamics is regulated in the nucleolus ...
Gettemans, Jan +3 more
core +2 more sources
Src-family kinases, expressed in a wide variety of cell types, are anchored to cellular membranes through posttranslational lipid modifications and involved in diverse cellular signalling.
Takao Morinaga +4 more
doaj +1 more source
Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. [PDF]
We studied the cell-surface delivery pathways of newly synthesized membrane glycoproteins in MDCK cells and for this purpose we characterized an endogenous apical integral membrane glycoprotein.
Le Bivic, A +3 more
core
The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. [PDF]
BackgroundThe current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.FindingsA/Anhui/1/2013 (H7N9) virus was administered by intranasal instillation to groups of mice and ...
Bao, Linlin +19 more
core +3 more sources
Effect of human activated NRAS on replication of delNS1 H5N1 influenza virus in MDCK cells
Background RAS, coded by ras proto-oncogenes, played an important role in signal transmission to regulate cell growth and differentiation. Host activation of RAS was significant for IFN-sensitive vaccinia virus (delE3L) or attenuate influenza virus in ...
Zou Wei +3 more
doaj +1 more source
Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. [PDF]
Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C.
Susan L Robertson +3 more
doaj +1 more source
Influenza A virus (IAV) infection poses a serious health threat and novel antiviral strategies are needed. Defective interfering particles (DIPs) can be generated in IAV infected cells due to errors of the viral polymerase and may suppress spread of wild
Arora, P. +6 more
core +2 more sources
Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R. +9 more
core +2 more sources
A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine [PDF]
Avian H9N2 and 2009 pandemic H1N1 (pH1N1) influenza viruses can infect pigs and humans, raising the concern that H9N2: pH1N1 reassortant viruses could emerge.
Ma, Wenjun +5 more
core +2 more sources
Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet unknown carrier was suggested in
Rune Nørgaard Rasmussen +3 more
doaj +1 more source

