Results 61 to 70 of about 41,345 (224)

Nfat5 is involved in the hyperosmotic regulation of Tmem184b: a putative modulator of ibuprofen transport in renal MDCK I cells

FEBS Open Bio, 2019
Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet unknown carrier was suggested in
Rune Nørgaard Rasmussen, Kenneth Vielsted Christensen, René Holm, Carsten Uhd Nielsen   +3 more
doaj   +1 more source

Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway

Brazilian Journal of Medical and Biological Research, 2011
The epithelial-mesenchymal transition (EMT) is involved in neoplastic metastasis, and the RON protein may be involved. In the present study, we determined the role and the mechanisms of action of RON in EMT in Madin-Darby canine kidney (MDCK) cells by ...
Xu Xiangming, Qian Yun, Zhang Guoliang, Lin Jianjiang, Teng Lisong   +4 more
doaj   +1 more source

MDCK cell line compound 2b

, 2019
MDCK cell line exposed to compound ...
zaid.alobaidi@uokerbala.edu.iq zaid.alobaidi@uokerbala.edu.iq (6703289)
core   +1 more source

Duck Orbivirus and Egg Production: A Newly Identified Duck Orbivirus Is the Etiological Agent of Egg Production Decline in Chinese Breeder Ducks

Animal Research and One Health, EarlyView.
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li, Jianhua Wang, Xuezhi Cui, Xinxing Chu, You Wang, Dongmin Hao, Mingqing Xu, Haixia Chang, Huihui Li, Mingtian Mao, Mian Wu, Chengguang Lu, Jing Tang, Suyun Liang, Zhanbao Guo, Zhengkui Zhou, Youxiang Diao, Shuisheng Hou, Yi Tang   +18 more
wiley   +1 more source

Polystyrene nanoparticle trafficking across MDCK-II [PDF]

Nanomedicine: Nanotechnology, Biology and Medicine, 2011
Polystyrene nanoparticles (PNP) cross rat alveolar epithelial cell monolayers via non-endocytic transcellular pathways. To evaluate epithelial cell type-specificity of PNP trafficking, we studied PNP flux across Madin Darby canine kidney cell II monolayers (MDCK-II).
Farnoosh, Fazlollahi, Susanne, Angelow, Nazanin R, Yacobi, Ronald, Marchelletta, Alan S L, Yu, Sarah F, Hamm-Alvarez, Zea, Borok, Kwang-Jin, Kim, Edward D, Crandall   +8 more
openaire   +2 more sources

MDCK cell line compound 2a

, 2019
MDCK cell line exposed to compound ...
zaid.alobaidi@uokerbala.edu.iq zaid.alobaidi@uokerbala.edu.iq (6703289)
core   +1 more source

Tumorigenicity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production.

PLoS ONE
Madin-Darby canine kidney (MDCK) cells are the recognized cell strain for influenza vaccine production. However, the tumorigenic potential of MDCK cells raises concerns about their use in biological product manufacturing.
Jiahao Zheng, Boran Li, Lanxin Jia, Jiayou Zhang, Zheng Gong, Yang Le, Xuanxuan Nian, Xuedan Li, Bo Liu, Daiguan Yu, Zhegang Zhang, Changgui Li   +11 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Heat shock proteins and the cellular response to osmotic stress [PDF]

, 2000
In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Lugmayr, Karin, Neuhofer, Wolfgang, Grünbein, Rita, Beck, Franz-X.   +3 more
core   +1 more source

Evaluation of near infrared dyes as markers of P-glycoprotein activity in tumors

Frontiers in Pharmacology, 2016
Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and poor patient prognosis.
Inessa Semenenko, Emma Portnoy, Mohammed AbouKaoud, Serge Guzy, Serge Guzy, Miri Shmuel, Gal Itzhak, Sara Eyal   +7 more
doaj   +1 more source