Cellular Aggregation Facilitates Anoikis in MDCK Cells
Anoikis is a specific type of apoptosis caused by the detachment of anchorage-dependent cells from their supportive matrix. Aggregation of suspended cells is believed to suppress anoikis. Here we describe the effects of cellular aggregation on anoikis in Madin-Darby canine kidney (MDCK) cells.
openaire +3 more sources
Amino Acids Regulate Transgene Expression in MDCK Cells
Gene expression and cell growth rely on the intracellular concentration of amino acids, which in metazoans depends on extracellular amino acid availability and transmembrane transport. To investigate the impact of extracellular amino acid concentrations on the expression of a concentrative amino acid transporter, we overexpressed the main kidney ...
Torrente M. +6 more
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Features 2016–2018 current human influenza A(H3N2) viruses circulating in Russia
Influenza A(H3N2) viruses demonstrate the highest level of evolutionary variability compared to other influenza viruses circulating in human population.
P. A. Petrova +7 more
doaj +1 more source
International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1) pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE [PDF]
The microneutralization assay is commonly used to detect antibodies to influenza virus, and multiple protocols are used worldwide. These protocols differ in the incubation time of the assay as well as in the order of specific steps, and even within ...
Engelhardt, OG +9 more
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Background Recent incidents where highly pathogenic influenza A H5N1 viruses have spread from avian species into humans have prompted the development of cell-based production of influenza vaccines as an alternative to or replacement of current egg-based ...
Duke Gregory M, Wang Zhaoti
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Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]
There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel +10 more
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Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain [PDF]
Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified.
Digard, Paul +12 more
core +4 more sources
Biodegradability and biocompatibility of copoly(butylene sebacate-co-terephthalate)s [PDF]
In the present study poly (butylene sebacate-co-terephthalate)s having different compositions were synthesized with a high yield and a random distribution by thermal transesterification of poly (butylene sebacate) and poly (butylene terephthalate ...
Faramarz Afshar Taromi, Faramarz Afshar +5 more
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Higher titers of some H5N1 and recent human H1N1 and H3N2 influenza viruses in Mv1 Lu vs. MDCK cells
Background The infectivity of influenza A viruses can differ among the various primary cells and continuous cell lines used for such measurements. Over many years, we observed that all things equal, the cytopathic effects caused by influenza A subtype ...
Daniels Deirdre E +6 more
doaj +1 more source
Mutational and secondary structural analysis of the basolateral sorting signal of the polymeric immunoglobulin receptor. [PDF]
The 17-juxtamembrane cytoplasmic residues of the polymeric immunoglobulin receptor contain an autonomous basolateral targeting signal that does not mediate rapid endocytosis (Casanova, J. E., G. Apodaca, and K. E. Mostov. Cell. 66:65-75).
Aroeti, B +4 more
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