Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies
Scientific Reports, 2022 The Madin-Darby canine kidney (MDCK) cell line is an in vitro model for influenza A virus (IAV) infection and propagation. MDCK-SIAT1 (SIAT1) and humanized MDCK (hCK) cell lines are engineered MDCK cells that express N-glycans with elevated levels of ...
Lauren Byrd-Leotis +6 more
doaj +3 more sources
The MDCK variety pack: choosing the right strain [PDF]
BMC Cell Biology, 2011 The MDCK cell line provides a tractable model for studying protein trafficking, polarity and junctions (tight, adherens, desmosome and gap) in epithelial cells.
Chalmers Andrew D +2 more
doaj +4 more sources
A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]
, 2012 © 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick +49 more
core +14 more sources
Cell Volume Fluctuations in MDCK Monolayers [PDF]
Biophysical Journal, 2015 Cells moving collectively in tissues constitute a form of active matter, in which collective motion depends strongly on driven fluctuations at the single-cell scale. Fluctuations in cell area and number density are often seen in monolayers, yet their role in collective migration is not known.
Steven M., Zehnder +4 more
openaire +3 more sources
Polystyrene nanoparticle trafficking across MDCK-II [PDF]
Nanomedicine: Nanotechnology, Biology and Medicine, 2011 Polystyrene nanoparticles (PNP) cross rat alveolar epithelial cell monolayers via non-endocytic transcellular pathways. To evaluate epithelial cell type-specificity of PNP trafficking, we studied PNP flux across Madin Darby canine kidney cell II monolayers (MDCK-II).
Farnoosh, Fazlollahi +8 more
openaire +2 more sources
Comparison of different cell substrates on the measurement of human influenza virus neutralizing antibodies. [PDF]
PLoS ONE, 2012 Eight cell lines were systematically compared for their permissivity to primary infection, replication, and spread of seven human influenza viruses. Cell lines were of human origin (Caco-2, A549, HEp-2, and NCI-H292), monkey (Vero, LLC-MK2), mink (Mv1 Lu)
Weiguo Zhai +6 more
doaj +1 more source
Heat shock proteins and the cellular response to osmotic stress [PDF]
, 2000 In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X. +3 more
core +1 more source
TGM2 inhibits the proliferation, migration and tumorigenesis of MDCK cells.
PLoS ONE, 2023 Madin-Darby canine kidney (MDCK) cells are one of the main cell lines used for influenza vaccine production due to their high virus yield and low mutation resistance.
Zhenyu Qiu +12 more
doaj +1 more source
Molecular characterization and phylogenetic analysis of a canine parvovirus isolate in India
Veterinární Medicína, 2009 Canine parvovirus 2 (CPV-2) is the causative agent of acute hemorrhagic enteritis and myocarditis in dogs. In this study the nucleotide sequence of the VP1/VP2 gene of a CPV isolate from India was analyzed and the phylogenetic relationship with other CPV
S. Nandi, S. Chidri, M. Kumar
doaj +1 more source
Distinct susceptibility and applicability of MDCK derivatives for influenza virus research. [PDF]
PLoS ONE, 2017 Madin-Darby Canine Kidney (MDCK) cells are widely utilized as a substrate for influenza virus isolation and propagation due to the high yields of virus.
Shih-Chao Lin +4 more
doaj +1 more source