Results 81 to 90 of about 33,185 (190)

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

Neurobiology of Disease, 2008
The pathogenesis of Alzheimer’s disease is characterized by aggregation of the amyloid-β protein (Aβ) into neurotoxic plaques. Recent in vivo studies have suggested the non-proteolytic clearance of Aβ via receptor-mediated transport across the blood ...
Babak Nazer, Soyon Hong, Dennis J. Selkoe   +2 more
doaj   +1 more source

Stability of vaccine strains of seasonal live attenuated influenza vaccines when adapted to MDCK cell culture

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Currently, the vast majority of influenza vaccines in the world are produced using developing chicken embryos as substrate, but there is an urgent necessity for transferring vaccine production to continuous cell lines, which would ensure ...
Victoria A. Matyushenko, Arina D. Kostromitina, Ekaterina A. Stepanova, Larisa G. Rudenko, Irina N. Isakova-Sivak   +4 more
doaj   +1 more source

Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1

Stem Cells International, 2017
Background. Mesenchymal stromal cells (MSC) are fibroblast-like multipotent cells capable of tissue-repair properties. Given the essentiality of tight junctions (TJ) in epithelial integrity, we hypothesized that MSC modulate TJ formation, via the AMP ...
P. Rowart, P. Erpicum, J.-M. Krzesinski, M. Sebbagh, F. Jouret   +4 more
doaj   +1 more source

ИСПОЛЬЗОВАНИЕ ПЕРЕВИВАЕМОЙ КУЛЬТУРЫ КЛЕТОК MDCK ДЛЯ ВЫДЕЛЕНИЯ ВИРУСА ГРИППА ПТИЦ

Ветеринарная патология, 2006
The technique of avian influenza virus isolation from samples of pathological material in the MDCK(Madin Darby canine cidney) cell culture was developed. The nineteen suspensions of organs were investigated.

doaj  

USP1 inhibits influenza A and B virus replication in MDCK cells by mediating RIG-I deubiquitination

Cellular and Molecular Life Sciences
The post-translational modification and stability regulation of RIG-I play critical roles in promoting IFN-I production and maintaining immune homeostasis.
Yuejiao Liao, Siya Wang, Tian Tang, Chengfang Li, Chenhao Yang, Liyuan Ma, Jin Ye, Jiamin Wang, Di Yang, Zilin Qiao, Zhongren Ma, Zhenbin Liu   +11 more
doaj   +1 more source

A Preclinical Model to Assess Intestinal Barrier Integrity Using Canine Enteroids and Colonoids

Biology
While two-dimensional (2D) cell cultures, such as Caco-2 and Madin–Darby canine kidney (MDCK) cells are widely used in a variety of biological models, these two-dimensional in vitro systems present inherent limitations in replicating the complexities of ...
Megan P. Corbett, Vojtech Gabriel, Vanessa Livania, David Díaz-Regañón, Abigail Ralston, Christopher Zdyrski, Dongjie Liu, Sarah Minkler, Hannah Wickham, Addison Lincoln, Karel Paukner, Todd Atherly, Maria M. Merodio, Dipak Kumar Sahoo, David K. Meyerholz, Karin Allenspach, Jonathan P. Mochel   +16 more
doaj   +1 more source

Osteopontin Expression in Polarized MDCK Cells

Kafkas Universitesi Veteriner Fakultesi Dergisi, 2014
TAŞÇENE N, İŞGÜDER Z, BERRIN SALMANOĞLU B   +2 more
openaire   +2 more sources

The Screening and Mechanism of Influenza-Virus Sensitive MDCK Cell Lines for Influenza Vaccine Production

Diseases
Influenza is a potentially fatal acute respiratory viral disease caused by the influenza virus. Influenza viruses vary in antigenicity and spread rapidly, resulting in seasonal epidemics.
Zhaona Yang, Shouzhi Yu, Ying Xu, Yuxiu Zhao, Lili Li, Jingjie Sun, Xin Wang, Yancen Guo, Yuntao Zhang   +8 more
doaj   +1 more source

Porcine influenza mAbs to H3, H5, and H7 hemagglutinins recognize H3 egg adapted site and target the HA stem. [PDF]

Discov Immunol
Cayol T, Villanueva-Hernández S, Briggs E, May C, McNee A, Vats A, Mittal B, Sadeyen JR, Iqbal M, Munir D, Di Placido M, Hammond JA, Townsend A, Rijal P, Paudyal B, Tchilian E.   +15 more
europepmc   +1 more source

Enhancing the stability of influenza a reporter viruses by recoding the gfp gene. [PDF]

Virol Sin
Hu J, Li J, Li Q, Jiang S, Cao Z, Chen H.   +5 more
europepmc   +1 more source