Results 121 to 130 of about 57,512 (227)

Comparison of Human and Canine P‐Glycoprotein Substrates at R, P, and H Binding Sites

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 2, Page 120-130, March 2026.
ABSTRACT P‐glycoprotein (P‐gp) greatly impacts substrate drug disposition, so much so that regulatory agencies recommend ascertaining the P‐gp status of active pharmaceutical ingredients (APIs) intended for human use. Arguably, the P‐gp status of drugs intended for canine patients is equally, if not more, important.
Neal S. Burke, Katrina L. Mealey
wiley   +1 more source

Adaptation of H2N2 influenza viruses with different receptor specificity to MDCK cells: opportunities for the development of a cell-based vaccine against pandemic H2N2 influenza

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. H2N2 influenza viruses caused a pandemic in 1957 due to the adaptation of avian influenza hemagglutinin from avian-type α2,3 to human-type α2,6 receptor specificity.
Victoria A. Matyushenko, Arina D. Kostromitina, Larisa G. Rudenko, Irina N. Isakova-Sivak   +3 more
doaj   +1 more source

Replication kinetics of novel swine influenza A viruses: an approach to vaccine production

Austral Journal of Veterinary Sciences
Novel swine Influenza A viruses (IAVs) have been described in South America. The objective of this study was to evaluate the replication kinetics of novel swine IAVs as a first step for vaccine production.
Rodrigo Tapia, Victor Neira, Rafael Medina   +2 more
doaj   +1 more source

Force-induced recruitment of cten along keratin network in epithelial cells. [PDF]

, 2019
The cytoskeleton provides structural integrity to cells and serves as a key component in mechanotransduction. Tensins are thought to provide a force-bearing linkage between integrins and the actin cytoskeleton; yet, direct evidence of tensin's role in ...
Cheah, Joleen S, Heinrich, Volkmar, Jacobs, Kyle A, Lo, Su Hao, Yamada, Soichiro   +4 more
core  

Replication of a Malaysian Strain Avian Influenza A Virus H5N1 in Madin-Darby Canine Kidney and African Green Monkey Kidney cells [PDF]

, 2016
The use of cell lines such as Madin-Darby Canine Kidney (MDCK) and African Green Monkey Kidney (Vero) cells in influenza vaccine production is much advocated presently as a safer alternative to chicken embryonated eggs. It is thus essential to understand
Sharifah Syed Hassan,, Tan, Toong Seng, Yap, Wei Boon   +2 more
core  

Cluster-cluster aggregation with particle replication and chemotaxy: a simple model for the growth of animal cells in culture

, 2010
Aggregation of animal cells in culture comprises a series of motility, collision and adhesion processes of basic relevance for tissue engineering, bioseparations, oncology research and \textit{in vitro} drug testing.
Alves, S. G., Martins, M. L.
core   +1 more source

Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF [PDF]

, 2019
学位記番号 ...
Nakasatomi, Masao, ナカサトミ, マサオ, 中里見, 征央   +2 more
core  

Transcriptional Analysis of lncRNA and Target Genes Induced by Influenza A Virus Infection in MDCK Cells. [PDF]

Vaccines (Basel), 2023
Liu G, Pei M, Wang S, Qiu Z, Li X, Ma H, Ma Y, Wang J, Qiao Z, Ma Z, Liu Z.   +10 more
europepmc   +1 more source

Mechanobiological mechanism of cyclic stretch-induced cell columnarization

Cell Reports
Summary: In vivo, epithelial cells maintain structural integrity under dynamic mechanical perturbations. To study this, we treated various epithelial cell lines with long-term cyclic stretch (CS).
Lun-Wei Lee, Gang-Hui Lee, I-Hsiu Su, Chia-Hsuan Lu, Keng-Hui Lin, Fu-Lai Wen, Ming-Jer Tang   +6 more
doaj   +1 more source

Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion. [PDF]

, 2018
Shear forces between cells occur during global changes in multicellular organization during morphogenesis and tissue growth, yet how cells sense shear forces and propagate a response across a tissue is unknown.
Garcia, Miguel A, Nelson, William James, Pruitt, Beth L, Sadeghipour, Ehsan   +3 more
core   +1 more source