Results 51 to 60 of about 1,892 (112)

Midkine Expression as a Candidate Biomarker to Predict the Recurrence of Stage IA Lung Adenocarcinoma

JTO Clinical and Research Reports
Background: Early recurrence limits the long-term survival of postoperative patients with stage IA lung adenocarcinoma (LUAD). This study aims to risk-stratify postoperative stage IA LUAD by means of the expression of Midkine (MDK). Materials and Methods:
Xiao Yang, PhD, Shuo Sun, BSc, Xunjie Kuang, BSc, Xianfeng Lu, MM, He Xiao, MM, Yi Duan, BSc, Yanli Xiong, MM, Di Zhang, BSc, Yu Xu, PhD, Jianwu Zhu, PhD, Mengxia Li, PhD   +10 more
doaj   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Pharmacokinetic Parameters of Oral Firocoxib, Oral Meloxicam, and Transdermal Flunixin in Meat Type Goats

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objective of this study was to determine and compare the pharmacokinetics of oral firocoxib, oral meloxicam, and transdermal flunixin (TD) in 44 adult, male castrated, crossbred goats. Pharmacokinetic (PK) analysis was performed for each goat in each phase using non‐compartmental methods with descriptive statistics reported.
Mikaela M. Weeder, Michael D. Kleinhenz, Christopher T. Culbertson, Emily J. Reppert, Kushan Kompalage, Ryan Tucker, Misty Bear, Andrew K. Curtis, Ally A. Nelson, Bailey R. Fritz, Payton Dahmer, Johann F. Coetzee   +11 more
wiley   +1 more source

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source

GPC2 promotes prostate cancer progression via MDK-mediated activation of PI3K/AKT signaling pathway

Functional & Integrative Genomics
Prostate cancer is a major medical problem for men worldwide. Advanced prostate cancer is currently incurable. Recently, much attention was paid to the role of GPC2 in the field of oncology. Nevertheless, there have been no investigations of GPC2 and its
Sijin Chen, Jiaxing Liao, Juhua Li, Saihui Wang   +3 more
semanticscholar   +1 more source

Protocol‐Agnostic Meta Key Distribution for Encrypted Wireless Communications Enabled by Space‐Time‐Coding Metasurface

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This paper presents a programmable metasurface‐based Meta Key Distribution (MKD) system for secure, protocol‐independent key exchange in indoor wireless settings. By embedding entropy into the wireless channel, it enables lightweight, compatible cryptographic key generation.
Xinyu Li, Long Chen, Guanxiong Shen, Kezhan Zhao, Ze Gu, Qian Ma, Jian Wei You, Tie Jun Cui   +7 more
wiley   +1 more source

Identification of MDK as a Hypoxia- and Epithelial–Mesenchymal Transition-Related Gene Biomarker of Glioblastoma Based on a Novel Risk Model and In Vitro Experiments

Biomedicines
Background: Tumor cells are commonly exposed to a hypoxic environment, which can easily induce the epithelial–mesenchymal transition (EMT) of tumor cells, further affecting tumor proliferation, invasion, metastasis, and drug resistance.
Minqi Xia, Shi’ao Tong, Ling Gao
semanticscholar   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Decentralizing genetic testing for biodiversity monitoring and biosurveillance with the Nucleic Acid Barcode Identification Tool (NABIT) and Molecular Development Kit (MDK)

bioRxiv
The escalating threats to biodiversity, public health, and food security posed by emerging infectious diseases and illegal wildlife trafficking requires novel approaches to biosurveillance. This paper introduces two innovations developed to address these
HR Holmes, M. Winters, C. Fang, G. Fotouhi, J. Mercader, DA Fox, Pme Bunje, A. Dehgan   +7 more
semanticscholar   +1 more source