Results 181 to 190 of about 64,512 (289)

MDM2/X mediates reduced apoptosis in the plateau zokor: a mechanism of high-altitude adaptation. [PDF]

J Zhejiang Univ Sci B
Zhang M, Li Y, Lin H, Yu T, Xia F, Chatoo M, Li K, Yu H, Nevo E, DU J, Zhao Y, Chen X.   +11 more
europepmc   +1 more source

Single‐Cell Transcriptomic Identification of Drug‐Tolerant Persister Mechanisms in Capecitabine‐Treated Triple‐Negative Breast Cancer

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype defined by the absence of estrogen receptor (ER), progesterone receptor (PR), and HER2 expression. This lack of receptors limits targeted therapies and contributes to high rates of recurrence.
Md Naiyem Islam, Md Kaziul Islam Sarkar Suja, Alif Al Takbir, Md. Kaderi Kibria   +3 more
wiley   +1 more source

Rapidly Progressive Dedifferentiated Liposarcoma of the Spermatic Cord: A Case Report. [PDF]

Int J Mol Sci
Rocha F, Figueroa-Emiliani J, Vargas-Castellanos E.   +2 more
europepmc   +1 more source

Experiment‐Anchored Abundance–Coverage Frontiers Define Conditional RHSVV Exposure Requirements in TP53‐Missense Tumors

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Mutant p53 accumulation may complement conformation‐sensitive RHSVV recognition, but the required exposure discrimination depends on tumor coverage and normal‐cell stress. We analyzed 809 tumors and 523 adjacent‐normal specimens from eight CPTAC cohorts.
Takehiro Ishikawa
wiley   +1 more source

Obstructive 12 cm Esophageal Liposarcoma Removed by Endoscopic Submucosal Dissection and Tissue Fragmentation. [PDF]

ACG Case Rep J
Turapov T, Qatomah A, Fang J, Ramai D.
europepmc   +1 more source

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang, Xue Wan, Shihe Wang, Honglan Dai, Huiling Zeng, Nan Chen, Xinxin Zhang   +6 more
wiley   +1 more source

β‐Arrestin1 Promotes Prostate Cancer Progression via Modulating ESRP1‐Mediated Alternative Splicing of CD44

MedComm – Oncology, Volume 5, Issue 4, December 2026.
β‐arrestin1 promotes prostate cancer progression by suppressing epithelial splicing regulatory protein 1 (ESRP1) expression and shifting CD44 alternative splicing toward CD44s and away from CD44v2 and CD44v6. These changes accompany increased N‐cadherin, decreased E‐cadherin, and enhanced epithelial–mesenchymal transition.
Sicheng Dong, Minlian Pan, Zhiqing He, Cong Wang, Yuhao Zhou, Jiayin Du, Tianyu Huang, Xue Wang, Xiaofeng Zhou, Zhixiong Zhang, Di Gu, Xiaolu Duan, Mengping Zhang   +12 more
wiley   +1 more source

Correction: Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source

Brigimadlin versus Doxorubicin in Advanced Dedifferentiated Liposarcoma: Efficacy, Safety, and Translational Data from Brightline-1, a Randomized Phase II/III Trial. [PDF]

Clin Cancer Res
Schöffski P, Sanfilippo R, Martín-Broto J, Kawai A, Desai J, LoRusso P, Maki RG, Jones RL, Blay JY, Smrke A, Abdul Razak A, Italiano A, Sebio A, Bahleda R, Lee YC, van der Graaf WTA, Zhang X, Biyukov T, Teufel M, Fu E, Lahmar M, Wagner AJ.   +21 more
europepmc   +1 more source