Results 191 to 200 of about 644,957 (254)

Harnessing MDM2-Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma. [PDF]

Adv Sci (Weinh)
Zhou J, Guan X, Li N, Zhang Y, Xie L, Huang X, Zhu Z, Ren Z, Yu X, Guo H, Wu Y, Ma L, Zheng S, Zhang J, Liu J, Lee VK, Chen W, Koeffler HP, Wang J, Han X, Chen Y, Xu L.   +21 more
europepmc   +1 more source

Fundamentals and emerging frontiers in p53-targeted drug development. [PDF]

Biochem Biophys Rep
Long HD, Zhang N, Wang WE, Ma YS, Liu FX, Chen ZY, Lu CN, Wang XF, Han N, Cai YF, Yang C, Tang XM, Yu H, Jiang H, Fu D, Chu KJ, Wu WG.   +16 more
europepmc   +1 more source

MDM2 Alters Cellular Iron Homeostasis by Promoting the Degradation of Proteins Involved in Iron Storage and Iron Export. [PDF]

Curr Issues Mol Biol
Shi Y, Zhang J.
europepmc   +1 more source

Targeting E3 ubiquitin ligases: Mechanistic breakthroughs and novel clinical translation pathways for tumor radioimmunotherapy. [PDF]

Mol Cancer
Yang Q, Xing X, Wang Y, Wang X, Han Y, Ren J, Zhang Z, Tang J, Zhao J.   +8 more
europepmc   +1 more source

RING finger E3 ubiquitin ligases: novel therapeutic opportunities in melanoma. [PDF]

Cell Mol Biol Lett
Zhang JF, Li LT, Yang YY, Zhang SC, Gao C, Zhu X, Xin H, Li XY.   +7 more
europepmc   +1 more source

MDM2 Drives Proteasome Inhibitor Resistance and Represents a TP53-Independent Therapeutic Vulnerability in Multiple Myeloma. [PDF]

Cells
Labrador M, Cozzubbo S, Porro M, Cumerlato M, Bandini C, Mereu E, Paradzik T, Donati B, Manicardi V, Ronchetti D, D'Agostino M, Larocca A, Gay F, Bruno B, Ciarrocchi A, Chatr-Aryamontri A, Neri A, Morelli E, Piva R.   +18 more
europepmc   +1 more source

Hypoxia-Inducible Factor-1α Stabilization Alleviates Hypoxia-Induced Temporomandibular Joint Osteoarthritis by Activating MDM2 to Suppression of p53 Signalling. [PDF]

Int Dent J
Chen Z, Cai J, Cai J, Yang X, Wang Z, Chen L, Chen S, Xu L, Wang H.   +8 more
europepmc   +1 more source

Beyond the Ribosome: The Expanding Role of the Nucleolus in Neurodegenerative Pathways. [PDF]

Mol Neurobiol
Iacono D, Feltis GC.
europepmc   +1 more source

Molecular mechanisms underlying liposarcoma subtype transition and proteasome-associated targeted interventions. [PDF]

J Transl Med
Liu J, Huo M, Wu S, Wang Z, Peng S, Fu Y.   +5 more
europepmc   +1 more source

The Evolving Landscape of Systemic Therapy for Liposarcoma. [PDF]

Cancers (Basel)
Kim HK, Sarkari A, Chow WA.
europepmc   +1 more source