Results 1 to 10 of about 100,852 (218)

MDR Tuberculosis Treatment [PDF]

open access: yesMedicina, 2022
Multidrug-resistant (MDR) tuberculosis (TB), resistant to isoniazid and rifampicin, continues to be one of the most important threats to controlling the TB epidemic. Over the last few years, there have been promising pharmacological advances in the paradigm of MDR TB treatment: new and repurposed drugs have shown excellent bactericidal and sterilizing ...
Juan Espinosa-Pereiro   +3 more
openaire   +5 more sources

Trends in Lung Cancer Incidence and Mortality (1990-2019) in the United States: A Comprehensive Analysis of Gender and State-Level Disparities

open access: yesJCO Global Oncology, 2023
PURPOSELung cancer is the leading cause of cancer-related deaths in the United States. This study aims to analyze lung cancer incidence, mortality, and related statistics from 1990 to 2019, focusing on national- and state-level trends and exploring ...
Chinmay T. Jani   +8 more
doaj   +1 more source

High-dose gatifloxacin-based shorter treatment regimens for MDR/RR-TB

open access: yesInternational Journal of Infectious Diseases, 2022
Setting: The shorter treatment regimen (STR) for multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) has achieved successful outcomes in many countries.
Qi Nie   +11 more
doaj   +1 more source

Organophosphate poisoning of Hyacinth Macaws in the Southern Pantanal, Brazil

open access: yesScientific Reports, 2021
The populations of hyacinth macaws (Anodorhynchus hyacinthinus), an emblematic species, have suffered declines due to many environmental factors. The Hyacinth Macaw Institute’s actions are showing positive outcomes for the conservation of A. hyacinthinus.
Eliane C. Vicente, Neiva M. R. Guedes
doaj   +1 more source

Unraveling hydrometeor mixtures in polarimetric radar measurements [PDF]

open access: yesAtmospheric Measurement Techniques, 2018
Radar-based hydrometeor classification typically comes down to determining the dominant type of hydrometeor populating a given radar sampling volume. In this paper we address the subsequent problem of inferring the secondary hydrometeor types present ...
N. Besic   +8 more
doaj   +1 more source

Bladder and bowel responses to lumbosacral epidural stimulation in uninjured and transected anesthetized rats

open access: yesScientific Reports, 2021
Spinal cord epidural stimulation (scES) mapping at L5-S1 was performed to identify parameters for bladder and bowel inhibition and/or contraction. Using spinally intact and chronic transected rats of both sexes in acute urethane-anesthetized terminal ...
Robert F. Hoey   +10 more
doaj   +1 more source

Antibiogram of Salmonella Isolates: Time to Consider Antibiotic Salvage [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Enteric fever is a major problem especially in developing countries. Timely and appropriate treatment plays a very important role in reducing the mortality. Fluoroquinolones and cephalosporins are the treatment options for enteric fever.
R. Sharvani   +4 more
doaj   +1 more source

Two new jatrophane diterpenes from the roots of Euphorbia nicaeensis [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
In the previous study fifteen jatrophane diterpenes were isolated from the Euphorbia nicaeensis latex. Fourteen of them have been shown to be potent P-glycoprotein (P-gp) inhibitor in two MDR cancer cells (NCI-H460/R and DLD1-TxR).
Krstić Gordana B.   +6 more
doaj   +1 more source

Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury

open access: yesNeurobiology of Disease, 2013
The endoplasmic reticulum (ER) stress response (ERSR) is activated to maintain protein homeostasis or induce apoptosis in the ER in response to distinct cellular insults including hypoxia, inflammation, and oxidative damage.
Sujata Saraswat Ohri   +2 more
doaj   +1 more source

Rifampicin resistance in new bacteriologically confirmed pulmonary tuberculosis patients in Cameroon: a cross-sectional survey

open access: yesBMC Research Notes, 2018
Objective In Cameroon, tuberculosis (TB) cases are diagnosed and treated within a nationwide network of 248 diagnostic and treatment centres. In 2016, the centers notified a total of 175 multidrug-resistant (MDR-)TB cases, most of them retreatment cases.
J. Noeske   +4 more
doaj   +1 more source

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