Results 31 to 40 of about 100,852 (218)

Evaluation of the Frequency of the Uropathogenic Escherichia coli Genotypes Resistant to Multidrug using the iucA, iucB, iucC, and iucD Siderophore Genes

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Urinary tract infection is one of the most common bacterial infections in humans, and Escherichia coli is one of the most important factors. Therefore, the present study aimed to evaluate the diversity of Europathogenic E.
Reihaneh Abroshan, Marjan Shaheli
doaj  

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

The growing concern of MDR/XDR bacteria in patients undergoing dialysis: a cross-sectional study

Počki
Background. Dialysis patients are at heightened risk for multidrug-resistant (MDR) and extensively drug-resistant (XDR) bacterial infections due to their vulnerability to infections and frequent exposure to healthcare environments.
Noor S. Kadhem, Ahmed Khassaf Atya
doaj   +1 more source

Detection of multidrug resistant Salmonella spp. from healthy and diseased broilers having potential public health significance

Journal of Advanced Biotechnology and Experimental Therapeutics, 2021
Multidrug resistant (MDR) Salmonella spp. poses significant global public health concern by causing food-borne infections. This study aimed to detect MDR Salmonella spp.
Mithun Talukder, Md. Saiful Islam, Samina Ievy, Md. Abdus Sobur, Fatimah Mohammed Ballah, Md. Najibullah, Md. Bahanur Rahman, Md. Tanvir Rahman, Mohammad Ferdousur Rahman Khan   +8 more
doaj   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Molecular detection of blaSHV gene in multidrug resistance of Klebsiella pneumoniae isolated from chicken egg shell swab from a traditional market in Surabaya

Open Veterinary Journal
Background: Contamination with Klebsiella pneumoniae in food ingredients, including eggs, causes various dangers because it threatens public health, because it acts as a multidrug resistance (MDR) bacteria, especially the extendedspectrum beta-lactamase
Azhari Athaillah Sulaiman, Mustofa Helmi Effendi, Leonardo Reza Srimaryanto, Aswin Rafif Khairullah, Pitaloka Kurniasari, Wiwiek Tyasningsih, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Saifur Rehman, Budiastuti Budiastuti, Daniah Ashri Afnani, Sheila Marty Yanestria, Katty Hendriana Priscilia Riwu, Agus Widodo   +13 more
doaj   +1 more source

Non-clinical isolates as potential reservoirs of antibiotic resistance in Port Harcourt, Nigeria

The Pan African Medical Journal, 2018
INTRODUCTION: Multidrug resistance (MDR) is a growing problem worldwide. This type resistance often arises due to the sequential acquisition of drug resistance determinants and subsequent clonal spread.
Kome Otokunefor, Paul Agbude, Tosanwumi Vincent Otokunefor   +2 more
doaj   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Short-Course Chemotherapy Regimens for Treatment of Multiple and Pre-Extensive Drug Resistant Tuberculosis in Combination with Surgery in Older Children and Adolescents

Туберкулез и болезни лёгких
The objective: to evaluate the effectiveness of short-curse chemotherapy regimens for treatment of MDR/pre-XDR tuberculosis in combination with surgery in older children and adolescents.Subjects and Methods.
E. S. Ovsyankina, L. V. Panova, E. A. Krushinskaya, M. A. Bagirov   +3 more
doaj   +1 more source

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

Advanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu, Yu Yang, Rui Zhao, Linwei Huang, Xingyu Qi, Min Wu, Jianliang Shen   +6 more
wiley   +1 more source