Results 101 to 110 of about 27,363 (307)

Existential and embodied presence—the meaning of peer support caring as experienced by breastfeeding peer support mothers in Sweden

International Journal of Qualitative Studies on Health & Well-Being
Purpose Many mothers face breastfeeding challenges that professional healthcare lacks the capacity to address, which can evoke exposedness and vulnerability. In Sweden, the non-profit Breastfeeding Support Organisation provide breastfeeding peer support.
Lina Palmér, Tora Nord, Marita Flisbäck   +2 more
doaj   +1 more source

Lost in an unknown terrain: a phenomenological contribution to the understanding of existential concerns as experienced by young women in Sweden

International Journal of Qualitative Studies on Health & Well-Being, 2019
Purpose: The aim of this study is to describe young women’s (16–25 years old) experiences of living with existential concerns for which they have sought support from healthcare professionals, teachers, family, or friends, among others.
Maria Lundvall, Elisabeth Lindberg, Ulrica Hörberg, Gunilla Carlsson, Lina Palmér   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Existential Humanistic Paradigm in Girish Karnad’s ‘’Hayavadana’’

, 2019
This paper attempts to interrogate Girish Karnad s Hayavadana from the perspective of existentialism relating the protagonist to main concerns of existential paradigm such as freedom choice responsibility finitude and death Individual s ...
Chandra Shekhar Dubey
core  

Living in Limbo: Existential Concerns Among Greek Young Adults

Youth
Existential concerns are particularly salient during emerging adulthood—a period marked by identity exploration, uncertainty, and developmental transitions. This qualitative study explores the existential anxieties of Greek young adults within the unique
Dimitrios Pavlidis, Panagiota Tragantzopoulou   +1 more
doaj   +1 more source

Religion and the Meaning of Life: An Existential Approach

Faith and Philosophy, 2020
Religion and the Meaning of Life: An Existential Approach, by Clifford Williams. Cambridge University Press, 2020. Pp vi + 189. $27.99 (paperback).
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The existential meaning of recovery

, 2002
Human beings are beings of meaning; we seek meaning in our lives and for our lives. Existential theory proposes that we are also beings faced with the responsibility of making free choices, choices designed to support each and every one of us to live an ...
Muir, Bruce Alexander
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source