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Recent Advances in Periodontal Regenerative Medicine: A Focus on the Role of Mechanical Stimulation [PDF]

Biomedicines
Periodontitis is a prevalent chronic inflammatory disease that leads to the progressive destruction of periodontal tissues and remains the primary cause of tooth loss worldwide.
Lidiia Grinchevskaia, Daria Revokatova, Mohammad Hadi Norahan, Alexey Senkovenko, Frederico David Alencar de Sena Pereira, Nastasia Kosheleva, Anastasia Shpichka, Peter Timashev   +7 more
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Role of SOST in Response to Mechanical Stimulation in Bone and Extraosseous Organs [PDF]

Biomolecules
Sclerostin (SOST) is a specific osteocyte protein. During the differentiation and proliferation of osteoblasts and osteoclasts, the high expression of SOST can inhibit bone formation and contribute to osteoporosis and the bone metastasis of malignant ...
Minyou Chen, Wenjing Li, Le Lei, Lingli Zhang   +3 more
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Mechanical stimulation prevents impairment of axon growth and overcompensates microtubule destabilization in cellular models of Alzheimer’s disease and related Tau pathologies [PDF]

Frontiers in Medicine
Alzheimer’s disease (AD) and related tauopathies such as frontotemporal dementia (FTD) or traumatic brain injury (TBI) are neurodegenerative disorders characterized by progressive loss of memory and cognitive function. The main histopathological features
Alice Alessandra Galeotti, Lorenzo Santucci, Jennifer Klimek, Jennifer Klimek, Mohamed Aghyad Al Kabbani, Mohamed Aghyad Al Kabbani, Hans Zempel, Hans Zempel, Vittoria Raffa   +8 more
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Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation [PDF]

Frontiers in Pharmacology
The mechanical stress environment in the temporomandibular joint (TMJ) is constantly changing due to daily mandibular movements. Therefore, TMJ tissues, such as condylar cartilage, the synovial membrane and discs, are influenced by different magnitudes ...
Yuqi Liu, Fangwen Jia, Kangya Li, Chao Liang, Xiao Lin, Wei Geng, Yanxi Li   +6 more
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Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology [PDF]

Frontiers in Molecular Biosciences
IntroductionCurrent in vitro intestinal models lack the mechanical forces present in the physiological environment, limiting their reliability for nanotoxicology studies.
Mattia Santoni, Giovanni Piccinini, Giovanni Piccinini, Giovanni Liguori, Maria Roberta Randi, Massimo Baroncini, Liliana Milani, Francesca Danesi   +7 more
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Data-Driven Dynamic Motion Planning for Practical FES-Controlled Reaching Motions in Spinal Cord Injury

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Functional electrical stimulation (FES) is a promising technology for restoring reaching motions to individuals with upper-limb paralysis caused by a spinal cord injury (SCI).
Derek N. Wolf, Antonie J. van den Bogert, Eric M. Schearer   +2 more
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Generation of a whole-brain hemodynamic response function and sex-specific differences in cerebral processing of mechano-sensation in mice detected by BOLD fMRI

Frontiers in Neuroscience, 2023
BOLD fMRI has become a prevalent method to study cerebral sensory processing in rodent disease models, including pain and mechanical hypersensitivity. fMRI data analysis is frequently combined with a general-linear-model (GLM) -based analysis, which uses
Hui-Fen Chen, Henriette Lambers, Nina Nagelmann, Martin Sandbrink, Daniel Segelcke, Esther Pogatzki-Zahn, Cornelius Faber, Bruno Pradier, Bruno Pradier   +8 more
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Bursa-Derived Cells Show a Distinct Mechano-Response to Physiological and Pathological Loading in vitro

Frontiers in Cell and Developmental Biology, 2021
The mechano-response of highly loaded tissues such as bones or tendons is well investigated, but knowledge regarding the mechano-responsiveness of adjacent tissues such as the subacromial bursa is missing.
Franka Klatte-Schulz, Franka Klatte-Schulz, Nicole Bormann, Nicole Bormann, Isabel Voss, Josephine Melzer, Aysha Schmock, Aysha Schmock, Christian H. Bucher, Christian H. Bucher, Kathi Thiele, Philipp Moroder, Melanie Haffner-Luntzer, Anita Ignatius, Georg N. Duda, Georg N. Duda, Britt Wildemann, Britt Wildemann   +17 more
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Integrated Perspective of Scaffold Designing and Multiscale Mechanics in Cardiac Bioengineering

Advanced NanoBiomed Research, 2021
Although progress has been made, a fully functional and transplantable cardiac patch is elusive due to several challenges. These challenges emanate from a nonoptimal understanding of different fields and expertise in biomedical, material, tissue ...
Lihua Lou, Kazue Orikasa Lopez, Pranjal Nautiyal, Arvind Agarwal   +3 more
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Porous Geometry Guided Micro-mechanical Environment Within Scaffolds for Cell Mechanobiology Study in Bone Tissue Engineering

Frontiers in Bioengineering and Biotechnology, 2021
Mechanobiology research is for understanding the role of mechanics in cell physiology and pathology. It will have implications for studying bone physiology and pathology and to guide the strategy for regenerating both the structural and functional ...
Feihu Zhao, Feihu Zhao, Feihu Zhao, Yi Xiong, Keita Ito, Keita Ito, Bert van Rietbergen, Sandra Hofmann, Sandra Hofmann   +8 more
doaj   +1 more source