Results 31 to 40 of about 3,418 (50)

Effect of stimulation frequency on osteogenic capability of electrical muscle stimulation

Journal of Biomechanical Science and Engineering, 2014
Exercise is effective as a preventive modality of osteoporosis because bone formation is accelerated by mechanical loading. However, elderly patients with osteoporosis are often difficult to exercise, which brings some risks of fractures during exercise ...
Shigeo M. TANAKA
doaj   +1 more source

A Novel Superparamagnetic‐Responsive Hydrogel Facilitates Disc Regeneration by Orchestrating Cell Recruitment, Proliferation, and Differentiation within Hostile Inflammatory Niche

Advanced Science
In situ disc regeneration is a meticulously orchestrated process, which involves cell recruitment, proliferation and differentiation within a local inflammatory niche.
Borui Xue, Yan Peng, Yongfeng Zhang, Shijie Yang, Yi Zheng, Huiling Hu, Xueli Gao, Beibei Yu, Xue Gao, Shengyou Li, Haining Wu, Teng Ma, Yiming Hao, Yitao Wei, Lingli Guo, Yujie Yang, Zhenguo Wang, Tingfeng Xue, Jin Zhang, Beier Luo, Bing Xia, Jinghui Huang   +21 more
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Engineering living root with mechanical stimulation derived from reciprocating compression in a double network hydrogel as elastic soil

Advanced Agrochem
The root system actively reacts to mechanical stimuli in its environment, transmitting mechanical signals to optimize the utilization of environmental resources.
Qiye Wu, Jinchun Xie, Junfu Li, Yongjun Men   +3 more
doaj   +1 more source

Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation

Frontiers in Pharmacology
The mechanical stress environment in the temporomandibular joint (TMJ) is constantly changing due to daily mandibular movements. Therefore, TMJ tissues, such as condylar cartilage, the synovial membrane and discs, are influenced by different magnitudes ...
Yuqi Liu, Fangwen Jia, Kangya Li, Chao Liang, Xiao Lin, Wei Geng, Yanxi Li   +6 more
doaj   +1 more source

Frequency and Resting Time Dependencies of Electrically-Induced Muscle Contraction Force

Journal of Biomechanical Science and Engineering, 2009
Physical exercise is a promising countermeasure for osteoporosis and strengthens skeletal muscle as well, resulting in a reduction of the risk of fall.
Shigeo M. TANAKA, Kanako KONDO
doaj   +1 more source

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science
Osteoarthritis (OA) is a joint disorder causing pain and disability, yet effective treatments are limited due to incomplete understanding of pathogenic mechanisms involving complex tissue interactions.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
doaj   +1 more source

CD73 and CD29 concurrently mediate the mechanically induced decrease of migratory capacity of mesenchymal stromal cells [PDF]

European Cells & Materials, 2011
The assumption that mesenchymal stromal cell (MSC)-based-therapies are capable of augmenting physiological regeneration processes has fostered intensive basic and clinical research activities.
A Ode, J Kopf, A Kurtz, K Schmidt-Bleek, P Schrade, P Kolar, F Buttgereit, K Lehmann, DW Hutmacher, GN Duda, G Kasper   +10 more
doaj  

Investigating the Effects of Mechanical Stimulation on Retinal Ganglion Cell Spontaneous Spiking Activity

Frontiers in Neuroscience, 2019
Mechanical forces are increasingly recognized as major regulators of several physiological processes at both the molecular and cellular level; therefore, a deep understanding of the sensing of these forces and their conversion into electrical signals are
Marica Marrese, Davide Lonardoni, Fabio Boi, Hedde van Hoorn, Alessandro Maccione, Stefano Zordan, Davide Iannuzzi, Luca Berdondini   +7 more
doaj   +1 more source

Enhanced solute transport and steady mechanical stimulation in a novel dynamic perifusion bioreactor increase the efficiency of the in vitro culture of ovarian cortical tissue strips

Frontiers in Bioengineering and Biotechnology
Introduction: We report the development and preliminary evaluation of a novel dynamic bioreactor to culture ovarian cortical tissue strips that leverages tissue response to enhanced oxygen transport and adequate mechanical stimulation. In vitro multistep
Gionata Fragomeni, Luigi De Napoli, Vincenza De Gregorio, Vincenzo Genovese, Vincenza Barbato, Giuseppe Serratore, Giuseppe Morrone, Angela Travaglione, Andrea Candela, Roberto Gualtieri, Riccardo Talevi, Gerardo Catapano   +11 more
doaj   +1 more source

Soft bioreactor systems: a necessary step toward engineered MSK soft tissue?

Frontiers in Robotics and AI
A key objective of tissue engineering (TE) is to produce in vitro funcional grafts that can replace damaged tissues or organs in patients. TE uses bioreactors, which are controlled environments, allowing the application of physical and biochemical cues ...
Nicole Dvorak, Zekun Liu, Pierre-Alexis Mouthuy   +2 more
doaj   +1 more source