Results 41 to 50 of about 506,255 (288)

Robotic trunk perturbation magnitude affects standing postural responses in individuals with motor complete spinal cord injury receiving epidural stimulation

Scientific Reports
After a severe spinal cord injury (SCI), the human spinal circuitry receiving epidural stimulation can generate lower limb postural responses to sensory inputs associated with trunk perturbation.
Enrico Rejc, Collin D. Bowersock, Tanvi Pisolkar, Simone Zaccaron, Claudia A. Angeli, Gail F. Forrest, Sunil Agrawal, Susan J. Harkema   +7 more
doaj   +1 more source

Mechanisms of osteocyte stimulation in osteoporosis [PDF]

Journal of the Mechanical Behavior of Biomedical Materials, 2016
Experimental studies have shown that primary osteoporosis' caused by oestrogen deficiency results in localised alterations in bone tissue properties and mineral composition. Additionally, changes to the lacunar-canalicular architecture surrounding the mechanosensitive osteocyte have been observed in animal models of the disease.
Verbruggen, S.W., Vaughan, T.J., McNamara, L.M.   +2 more
openaire   +6 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Modulation of interhemispheric inhibition and motor learning by different intensities of bilateral transcranial direct current stimulation in healthy adults

Scientific Reports
Interhemispheric inhibition (IHI) plays a crucial role in performing unilateral hand movements. Transcranial direct current stimulation (tDCS) has been shown to modulate IHI and enhance motor learning, but the most effective stimulation intensity remains
Thatchaya Prathum, Julien Dauguet, Irin Apiworajirawit, Benchaporn Aneksan, Siriwan Hoisan, Arruck Tragangoon, Vorasith Siripornpanich, Wanalee Klomjai   +7 more
doaj   +1 more source

Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray [PDF]

, 2017
The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in
Bruchas, Michael R, Copits, Bryan A, Gereau, Robert W, IV, Gomez, Adrian M, Grajales-Reyes, Jose G, O\u27Brien, Daniel E, Samineni, Vijay K, Trigg, Sarah L   +7 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Mobile mechanical signal generator for macrophage polarization

Exploration, 2023
The importance of mechanical signals in regulating the fate of macrophages is gaining increased attention recently. However, the recently used mechanical signals normally rely on the physical characteristics of matrix with non‐specificity and instability
Jiamiao Jiang, Fei Wang, Weichang Huang, Jia Sun, Yicheng Ye, Juanfeng Ou, Meihuan Liu, Junbin Gao, Shuanghu Wang, Dongmei Fu, Bin Chen, Lu Liu, Fei Peng, Yingfeng Tu   +13 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Inventory of personal factors influencing conditioned pain modulation in healthy people: a systematic literature review [PDF]

, 2015
Background: Conditioned pain modulation (CPM) is believed to play an important role in the development and exacerbation of chronic pain, because dysfunction of CPM is associated with a shift in balance between pain facilitation and pain inhibition.
Calders, Patrick, Crombez, Geert, Goubert, Dorien, Goudman, Lisa, Hermans, Linda, Meeus, Mira, Van Oosterwijck, Jessica   +6 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source