Results 41 to 50 of about 3,418 (50)

Role of SOST in Response to Mechanical Stimulation in Bone and Extraosseous Organs

Biomolecules
Sclerostin (SOST) is a specific osteocyte protein. During the differentiation and proliferation of osteoblasts and osteoclasts, the high expression of SOST can inhibit bone formation and contribute to osteoporosis and the bone metastasis of malignant ...
Minyou Chen, Wenjing Li, Le Lei, Lingli Zhang   +3 more
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Chromium Oxide Nanoparticle Impaired Osteogenesis and Cellular Response to Mechanical Stimulus

International Journal of Nanomedicine, 2021
Jian Chen,1,* Jing Ding,1,* Yuanhao Wu,2 Shuqiong Zhang,3 Naisheng Zheng,3 Junyao Yang,3 Jing Xu1 1Department of Paediatric Orthopaedics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200092, People’s Republic of ...
Chen J, Ding J, Wu Y, Zhang S, Zheng N, Yang J, Xu J   +6 more
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Mechanical stimulation prevents impairment of axon growth and overcompensates microtubule destabilization in cellular models of Alzheimer’s disease and related Tau pathologies

Frontiers in Medicine
Alzheimer’s disease (AD) and related tauopathies such as frontotemporal dementia (FTD) or traumatic brain injury (TBI) are neurodegenerative disorders characterized by progressive loss of memory and cognitive function. The main histopathological features
Alice Alessandra Galeotti, Lorenzo Santucci, Jennifer Klimek, Jennifer Klimek, Mohamed Aghyad Al Kabbani, Mohamed Aghyad Al Kabbani, Hans Zempel, Hans Zempel, Vittoria Raffa   +8 more
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Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats

Journal of Pain Research, 2009
Guy Hans1,2,3, Kristof Deseure2,3, Marcel Vercauteren1,2,31Multidisciplinary Pain Center; 2Department of Anesthesiology, Antwerp University Hospital, Edegem, Belgium; 3Laboratory of Anesthesiology and Pain Research, University of Antwerp, Wilrijk ...
Guy Hans, Kristof Deseure, Marcel Vercauteren   +2 more
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Multi-axial mechanical stimulation of tissue engineered cartilage: Review [PDF]

European Cells & Materials, 2007
The development of tissue engineered cartilage is a promising new approach for the repair of damaged or diseased tissue. Since it has proven difficult to generate cartilaginous tissue with properties similar to that of native articular cartilage, several
S D Waldman, D C Couto, M D Grynpas, R M Pilliar, R A Kandel   +4 more
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Sliding contact loading enhances the tensile properties of mesenchymal stem cell-seeded hydrogels [PDF]

European Cells & Materials, 2012
The primary goal of cartilage tissue engineering is to recapitulate the functional properties and structural features of native articular cartilage.
AH Huang, BM Baker, GA Ateshian, RL Mauck   +3 more
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Systemic Administration of Docosahexaenoic Acid Suppresses Trigeminal Secondary Nociceptive Neuronal Activity in Rats

International Journal of Translational Medicine
Background and Objectives: Docosahexaenoic acid (DHA) has been shown to modulate various voltage-gated ion channels and both excitatory and inhibitory synapses. Nonetheless, its exact effect on nociceptive signaling in the trigeminal system has yet to be
Hanano Takahashi, Yukito Sashide, Mamoru Takeda   +2 more
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Focal mechanical vibration motor effects on the finger tapping in healthy volunteers

Frontiers in Sports and Active Living
IntroductionFocal mechanical vibration is a therapeutic intervention based on oscillatory mechanical vibrations applied to specific anatomical structures.
Tommaso Di Libero, Angelo Rodio, Chiara Carissimo, Gianni Cerro, Cecilia Provenzale, Annalisa D’Ermo, Guido Maria Filippi, Vito Enrico Pettorossi, Luigi Ferrigno, Enrico Marchetti, Luigi Fattorini   +10 more
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Bioenergy sorghum stems respond to mechanical stimulation with tissue-specific modifications in hormone homeostasis and anatomical traits

Frontiers in Plant Science
Sorghum [Sorghum bicolor (L.) Moench] is a promising and highly productive bioenergy crop but remains susceptible to stem lodging, typically caused by severe weather-related mechanical forces like wind and rain.
Qing Li, Qing Li, Omid Zargar, Sungkyu Park, Matt Pharr, Anastasia Muliana, Tesfamichael H. Kebrom, Scott A. Finlayson   +7 more
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Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi‐Axial Perspective of Mechanical, Immune, and Metabolic Pathways

JOR Spine
Background The senescence of nucleus pulposus cells (NPCs) at the heart of the pathogenesis of intervertebral disc degeneration (IVDD), which causes low back pain. Abnormal mechanical stress causes intracellular Ca2+ overload by activating the Piezo‐type
Yunbo Yang, Haoming Li, Junhui Zuo, Fei Lei   +3 more
doaj   +1 more source