Results 71 to 80 of about 3,260,986 (243)

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science
Osteoarthritis (OA) is a joint disorder causing pain and disability, yet effective treatments are limited due to incomplete understanding of pathogenic mechanisms involving complex tissue interactions.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
doaj   +1 more source

Engineering living root with mechanical stimulation derived from reciprocating compression in a double network hydrogel as elastic soil

Advanced Agrochem
The root system actively reacts to mechanical stimuli in its environment, transmitting mechanical signals to optimize the utilization of environmental resources.
Qiye Wu, Jinchun Xie, Junfu Li, Yongjun Men   +3 more
doaj   +1 more source

Frequency and Resting Time Dependencies of Electrically-Induced Muscle Contraction Force

Journal of Biomechanical Science and Engineering, 2009
Physical exercise is a promising countermeasure for osteoporosis and strengthens skeletal muscle as well, resulting in a reduction of the risk of fall.
Shigeo M. TANAKA, Kanako KONDO
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation

Frontiers in Pharmacology
The mechanical stress environment in the temporomandibular joint (TMJ) is constantly changing due to daily mandibular movements. Therefore, TMJ tissues, such as condylar cartilage, the synovial membrane and discs, are influenced by different magnitudes ...
Yuqi Liu, Fangwen Jia, Kangya Li, Chao Liang, Xiao Lin, Wei Geng, Yanxi Li   +6 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats

, 2009
Guy Hans1,2,3, Kristof Deseure2,3, Marcel Vercauteren1,2,31Multidisciplinary Pain Center; 2Department of Anesthesiology, Antwerp University Hospital, Edegem, Belgium; 3Laboratory of Anesthesiology and Pain Research, University of Antwerp, Wilrijk ...
Kristof Deseure, Vercauteren, Marcel, Deseure, Kristof, Marcel Vercauteren, Hans, Guy, Guy Hans   +5 more
core  

Robotic induction of neuromodulation via paired brain stimulation with mechanical stimulation

, 2020
Recent studies indicate that neural plasticity may contribute to functional recovery after a stroke where long-term potentiation (LTP) has been regarded as a contributor to motor learning as it strengthens excitatory synapses.
Kim, Euisun
core  

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research
Tendon injuries affect millions each year, yet effective repair remains limited by the tissue's avascular nature and complex mechanobiology. An anisotropic electrospun scaffold functionalized with GDF‐7‐loaded mesoporous silica nanoparticles (MSNs) is ...
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
doaj   +1 more source

CD73 and CD29 concurrently mediate the mechanically induced decrease of migratory capacity of mesenchymal stromal cells [PDF]

European Cells & Materials, 2011
The assumption that mesenchymal stromal cell (MSC)-based-therapies are capable of augmenting physiological regeneration processes has fostered intensive basic and clinical research activities.
A Ode, J Kopf, A Kurtz, K Schmidt-Bleek, P Schrade, P Kolar, F Buttgereit, K Lehmann, DW Hutmacher, GN Duda, G Kasper   +10 more
doaj