Results 191 to 200 of about 1,725,788 (328)

Stability of arterial blood gas samples after delayed analysis and mechanical stress. [PDF]

PLoS One
Gutermuth M, Ihmsen H, Krischke F, Moritz A, Prottengeier J.   +4 more
europepmc   +1 more source

Data from Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II

, 2023
Maria Kalli, Ruxuan Li, Gordon B. Mills, Triantafyllos Stylianopoulos, Ioannis K. Zervantonakis   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Mechanical Stress and Protective Mechanisms in Podocytes: Insights into Hypertensive Nephropathy. [PDF]

Int J Mol Sci
Du SJ, Huang W, Hao Y, Zhang C, He FF.
europepmc   +1 more source

Effect of initial normal stress and normal stiffness on the shear mechanical behavior of rough rock joints

Hao Yu, Shuchen Li, Meng Wang, Yingsen Wang, Yuwei Wang, Richeng Liu, Luyi Xing   +6 more
openalex   +1 more source

Possibility of Odontoblasts Activity Up-Regulation due to Orthodontic Mechanical Stress in Mice

, 2010
Keisuke Nakano, Rina Muraoka, Mihoko Tomida, Sachiko Matsuura, Norimasa Okafuji, Chong Huat Siar, Toshiyuki Kawakami   +6 more
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity. [PDF]

Adv Sci (Weinh)
Gehwolf R, Tempfer H, Cesur NP, Wagner A, Traweger A, Lehner C.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intracellular Mechanical Stress-Mediated Autophagy Cell Death via Nanospikes for Cancer Treatment. [PDF]

Adv Sci (Weinh)
Li Y, Guo Z, Fan J, Zhou R, Li J, Hu Z, Gu W, Zheng M, Xu C, Tang Y, Chen C, Cheng Y.   +11 more
europepmc   +1 more source