Results 81 to 90 of about 7,453,208 (377)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Deformation effects in glycinium phosphite ferroelectric
Condensed Matter Physics, 2018 To study the effects appearing under mechanical stresses, we have used the model of glycinium phosphite ferroelectric, modified by taking into account the piezoelectric coupling of ordering structure elements with lattice strains.
I.R. Zachek +2 more
doaj +1 more source
Sarcomere Mechanics in the Stress Fiber [PDF]
Biophysical Journal, 2009 Actin filaments inside endothelial cells assemble into tensed bundles called stress fibers. Stress fibers are observed in vivo in a variety of tissues including the aorta, the heart, the spleen, the eye, and hair follicles. Sarcomeres are the force generating units of stress fibers and are responsible for generating intracellular tension.
Tanmay P. Lele +2 more
openaire +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Exercise for osteoporosis: A literature review of pathology and mechanism
Frontiers in Immunology, 2022 Osteoporosis (OP) is a disease that weakens bones and has a high morbidity rate worldwide, which is prevalent among the elderly, particularly, women of postmenopausal age.
Lin Zhang +5 more
doaj +1 more source
Mechanisms of Cellular Stress Adaptation
, 2020 Cells need to continuously adapt to changes in their environment, such as a rise in temperature. Heat causes proteins to unfold, thereby compromising intracellular processes and structures. To brace against this menace, organisms have evolved a highly conserved protective programme, the so-called heat shock response (HSR).
openaire +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Bioscience Reports, 2016 Mechanical stress which would cause deleterious adhesive effects on podocytes is considered a major contributor to the early progress of diabetic nephropathy (DN).
Dong Li +6 more
semanticscholar +1 more source
Proline Mechanisms of Stress Survival [PDF]
Antioxidants & Redox Signaling, 2013 The imino acid proline is utilized by different organisms to offset cellular imbalances caused by environmental stress. The wide use in nature of proline as a stress adaptor molecule indicates that proline has a fundamental biological role in stress response.
Liang, Xinwen +3 more
openaire +3 more sources