Results 41 to 50 of about 10,501,738 (419)

Chiral separation in microflows [PDF]

open access: yes, 2005
Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology and belongs ...
A. J. Lichtenberg   +8 more
core   +2 more sources

Molecular Biology of the Cell

open access: yesColor Atlas of Clinical Hematology, 1990
Much of the research in the Pringle laboratory exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis ...
S. Dolomatov, E. Ageeva, Walery Zukow
semanticscholar   +1 more source

Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy

open access: yesNature Communications, 2020
Fukutin-related protein (FKRP) catalyses the addition of ribitol-phosphate (RboP) to the O-mannosyl glycan of α-dystroglycan and mutations in FKRP cause dystroglycanopathy. Here the authors provide insights into its oligomerization and recognition of the
Naoyuki Kuwabara   +11 more
doaj   +1 more source

Steering proton migration in hydrocarbons using intense few-cycle laser fields [PDF]

open access: yes, 2016
Proton migration is a ubiquitous process in chemical reactions related to biology, combustion, and catalysis. Thus, the ability to control the movement of nuclei with tailored light, within a hydrocarbon molecule holds promise for far-reaching ...
Alnaser, A. S.   +12 more
core   +2 more sources

Physics of liquid crystals in cell biology [PDF]

open access: yesarXiv, 2021
The last decade has witnessed a rapid growth in understanding of the pivotal roles of mechanical stresses and physical forces in cell biology. As a result an integrated view of cell biology is evolving, where genetic and molecular features are scrutinized hand in hand with physical and mechanical characteristics of cells. Physics of liquid crystals has
arxiv  

G-quadruplexes and their regulatory roles in biology

open access: yesNucleic Acids Research, 2015
‘If G-quadruplexes form so readily in vitro, Nature will have found a way of using them in vivo’ (Statement by Aaron Klug over 30 years ago). During the last decade, four-stranded helical structures called G-quadruplex (or G4) have emerged from being a ...
D. Rhodes, H. Lipps
semanticscholar   +1 more source

Effect of exosomal miRNA on cancer biology and clinical applications

open access: yesMolecular Cancer, 2018
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely present in various body fluids. Recently, microRNAs (miRNAs) have been identified in exosomes, the biogenesis, release, and uptake of which may involve the endosomal ...
Zhenqiang Sun   +9 more
semanticscholar   +1 more source

Is synthetic biology mechanical biology?

open access: yesHistory and Philosophy of the Life Sciences, 2015
A widespread and influential characterization of synthetic biology emphasizes that synthetic biology is the application of engineering principles to living systems. Furthermore, there is a strong tendency to express the engineering approach to organisms in terms of what seems to be an ontological claim: organisms are machines.
openaire   +4 more sources

αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression

open access: yesCell Reports, 2023
Summary: Increased metabolic activity usually provides energy and nutrients for biomass synthesis and is indispensable for the progression of the cell cycle.
Yanting Yang   +5 more
doaj  

Identification of the effect of cisplatin on the transcriptome of human hepatocellular carcinoma cell lines [PDF]

open access: yesJichu yixue yu linchuang
Objective To investigate the effect of cisplatin treatment on the transcriptional level of human liver cancer cells by conducting transcriptome sequencing analysis after treating human liver cancer cell lines with different concentrations of cisplatin ...
GUO Xin, JI Mengdie, WANG Qi, LI Xueyuan, CHEN Yang
doaj   +1 more source

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