Results 11 to 20 of about 1,326,724 (170)
Marine Drugs, 2018 A novel wild-type recombinant cold-active α-d-galactosidase (α-PsGal) from the cold-adapted marine bacterium Pseudoalteromonas sp. KMM 701, and its mutants D451A and C494N, were studied in terms of their structural, physicochemical, and ...
Irina Bakunina +8 more
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Oritavancin: Mechanism of Action [PDF]
Clinical Infectious Diseases, 2012 Oritavancin is a semisynthetic lipoglycopeptide analogue of vancomycin that contains the heptapeptide core common to all glycopeptides. It differs from vancomycin by the presence of a hydrophobic N-4-(4-chlorophenyl)benzyl (also referred to as 4'-chlorobiphenylmethyl) substituent on the disaccharide sugar, the addition of a 4-epi-vancosamine ...
George G, Zhanel +2 more
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Marine Drugs, 2018 A new melatonin analogue 6-hydroxy-N-acetyl-β-oxotryptamine (1) was isolated from the marine-derived fungus Penicillium sp. KMM 4672. It is the second case of melatonin-related compounds isolation from microfilamentous fungi.
Ekaterina A. Yurchenko +6 more
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Heparins: Mechanism of Action and Application in Acute Pancreatitis
Львівський клінічний вісник, 2015 Introduction. Heparin is a glycosaminoglycan composed of chains of alternating d-glucosamine and uronic acid residues. Its major anticoagulant effect is attributed to a unique pentasaccharide structure.
Chooklin S., Pidhirnyy B., Chuklin S.
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Analgesic choice in dentistry. Part I: The mechanism of action
Brazilian Journal of Oral Sciences, 2015 Analgesics are frequently used in dentistry for the management of dental pain. Dental clinicians should choose the medicine based on its mechanism of action and toxicity, to promote a successful analgesic effect as well as comfort to the patient.
Filipe Polese Branco +3 more
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An Exploration of the Mechanism of Action of an Equine-Assisted Intervention
Animals, 2019 Though long alluded to, there is now an accumulation of evidence of the vital contribution that emotion makes to learning. Within this broad advance in understanding is a growing body of research emphasising the embodied nature of this emotion-based ...
Ann Hemingway +4 more
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Pharmaceutics, 2021 We describe the design and attributes of a linear pentapeptide-like derivative (C14(ω5)OOc10O) screened for its ability to elicit bactericidal competences of plasma constituents against Gram-negative bacteria (GNB).
Fadia Zaknoon, Ohad Meir, Amram Mor
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BIOMOLECULAR MECHANISM OF ANTI EPILEPTIC DRUGS
Malang Neurology Journal, 2018 Epilepsy therapy is almost always chronic and often used more than one drug. Currently, antiepileptic drugs are still the mainstay of therapy for epilepsy. An understanding of the pharmacodynamics and pharmacokinetics of these drugs would be very helpful
Machlusil Husna +1 more
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Alitretinoin in treatment of chronic hand eczema – mechanism of action
Przegląd Dermatologiczny, 2016 Hand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants, often give unsatisfactory results,
Maria Matejko, Beata Kręcisz
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Properties and synthesis of milrinone [PDF]
Hemijska Industrija, 2013 Milrinone, 1,6-dihydro-2-methyl-6-oxo-[3,4’-bipyridine]-5-carbonitrile, is a positive inotropic cardiotonic agent with vasodilator properties that acts as selective phosphodiesterase 3 inhibitor in cardiac and vascular smooth muscle.
Mirković Jelena M. +2 more
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