Results 11 to 20 of about 3,888,432 (355)
Calcifediol: Mechanisms of Action
Nutrients, 2023 Due to its essential role in calcium and phosphate homeostasis, the secosteroid hormone calcitriol has received growing attention over the last few years. Calcitriol, like other steroid hormones, may function through both genomic and non-genomic mechanisms.
Simone Donati +7 more
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Mechanisms of Action of Adjuvants [PDF]
Frontiers in Immunology, 2013 Adjuvants are used in many vaccines, but their mechanisms of action are not fully understood. Studies from the past decade on adjuvant mechanisms are slowly revealing the secrets of adjuvant activity. In this review, we have summarized the recent progress in our understanding of the mechanisms of action of adjuvants.
Awate, Sunita +2 more
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Vagal Blocking for Obesity Control : a Possible Mechanism-Of-Action [PDF]
, 2016 14 September 2016 Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action Helene Johannessen, David Revesz, Yosuke Kodama, Nikki Cassie, Karolina P Skibicka, Perry Barrett, Suzanne Dickson, Jens Holst, Jens Rehfeld, Geoffrey van ...
Adan, Roger +14 more
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Bisphosphonates: Mechanisms of Action [PDF]
Endocrine Reviews, 1998 The geminal bisphosphonates are a class of drug, developed in the last 30 years, characterised by a P-C-P bond. Consequently, they are analogues of pyrophosphate but are resistant to chemical and enzymatic hydrolysis. The bisphosphonates bind strongly to hydroxyapatite crystals and inhibit their formation and dissolution. This physicochemical effect on
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Marine Drugs, 2018 A novel wild-type recombinant cold-active α-d-galactosidase (α-PsGal) from the cold-adapted marine bacterium Pseudoalteromonas sp. KMM 701, and its mutants D451A and C494N, were studied in terms of their structural, physicochemical, and ...
Irina Bakunina +8 more
doaj +1 more source
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
, 2018 Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo +90 more
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Marine Drugs, 2018 A new melatonin analogue 6-hydroxy-N-acetyl-β-oxotryptamine (1) was isolated from the marine-derived fungus Penicillium sp. KMM 4672. It is the second case of melatonin-related compounds isolation from microfilamentous fungi.
Ekaterina A. Yurchenko +6 more
doaj +1 more source
Glucocorticoids for human skin: New aspects of the mechanism of action [PDF]
, 2005 Topical glucocorticoids have always been considered first-line drugs for inflammatory diseases of the skin and bronchial system. Applied systemically, glucocorticoids are used for severe inflammatory and immunological diseases and the inhibition of ...
Ahmed, M. +4 more
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Open inflation from quantum cosmology with a strong nonminimal coupling [PDF]
, 1998 We propose the mechanism of quantum creation of the open Universe in the observable range of values of $\Omega$. This mechanism is based on the no-boundary quantum state with the Hawking-Turok instanton applied to the model with a strong nonminimal ...
A.O. Barvinsky +44 more
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Structural basis of complement membrane attack complex formation [PDF]
, 2015 In response to complement activation, the membrane attack complex (MAC) assembles from fluid-phase proteins to form pores in lipid bilayers. MAC directly lyses pathogens by a ‘multi-hit’ mechanism; however, sublytic MAC pores on host cells activate ...
Bubeck, D +3 more
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