Results 261 to 270 of about 4,146,035 (404)

THE MECHANISM OF THE SPARING ACTION OF CARBOHYDRATES ON PROTEIN METABOLISM

, 1916
R.A. Kocher
openalex   +1 more source

SOME OBSERVATIONS ON THE MECHANISM OF DRUG ACTION: A STUDY IN PHARMACO-DYNAMICS [PDF]

, 1922
O. C. M. Davis
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Integrated network pharmacology reveals the mechanism of action of Xianlinggubao prescription for inflammation in osteoarthritis. [PDF]

BMC Complement Med Ther
Hou J, Li Y, Zhang Y, Yang N, Chen B, Ma G, Zhu N.   +6 more
europepmc   +1 more source

The role and mechanism of action of menthol in topical analgesic products

Journal of Clinical Pharmacy and Therapeutics, 2018
J. Pergolizzi, Robert Taylor, J. LeQuang, Robert B. Raffa, Robert B. Raffa   +4 more
semanticscholar   +1 more source

ON THE MECHANISM OF ACTION OF PHOSPHOLIPASE A [PDF]

Biochemical Journal, 1963
openaire   +3 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Metabolomics provides novel understanding of Melissa officinalis mechanism of action ensuring its calming effect on dogs. [PDF]

BMC Vet Res
Roy AS, Aberkane FZ, Cisse S, Guibert A, Richard D, Lerouzic M, Suor-Cherer S, Boisard S, Guilet D, Benarbia MEAB, Mallem MY.   +10 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Temperature dependence of adhesive friction properties of rubber asphalt mortar and its mechanism of action. [PDF]

PLoS One
Du Y, Li N, Yang M, Shan S, Dou H, Chen Y, Liu X.   +6 more
europepmc   +1 more source