Results 121 to 130 of about 41,665 (257)

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Coding of mechanical pain by myelinated and unmyelinated nociceptors in human hairy skin. [PDF]

Pain Rep
Bouchatta O, Thorell O, Marshall AG, Rezaei M, Barakat A, McIntyre S, Gerling GJ, Mahns DA, Olausson H, Nagi SS.   +9 more
europepmc   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu, L. Madden Brewster, Travis D. Gibbons, James D. Anholm, Michael Stembridge, Philip N. Ainslie, Jay M. J. R. Carr   +6 more
wiley   +1 more source

What Is Inside the Sinus Tarsi? Mechanoreceptor Distribution, Typing and Clinical Relevance-A Histological and Immunohistochemical Synthesis. [PDF]

Biomedicines
Arceri A, Mazzotti A, Di Paola G, Sgubbi F, Langone L, Zielli SO, Veronesi F, Giavaresi G, Mora P, Faldini C.   +9 more
europepmc   +1 more source

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

The Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel, Nisha Vastani, Clive Gentry, Andreas Goebel, Stuart Bevan, David A. Andersson   +5 more
wiley   +1 more source

Peripheral mechanisms of tactile sensation in fish. [PDF]

Curr Opin Neurobiol
Tan K, Gracheva EO, Bagriantsev SN.
europepmc   +1 more source

Vibrotactile intensity perception: Predominant influence of afferents recruited remote from stimulus site

The Journal of Physiology, EarlyView.
Abstract figure legend We delivered trains of brief mechanical pulses to the fingertips of subjects to investigate vibrotactile intensity perception. Some stimuli consisted of bursts of up to four pulses. Simulated responses of the tactile afferent population across the hand revealed that afferents innervating the skin directly under the probe reliably
Kevin K. W. Ng, Ingvars Birznieks, Richard M. Vickery   +2 more
wiley   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

Rewarding touch limits lifespan through neural to intestinal signaling. [PDF]

Proc Natl Acad Sci U S A
Kitto ES, Beydoun S, Leiser SF.
europepmc   +1 more source

Affective CT‐touch attenuates cortical responses and subjective attention during temporal summation of second pain

The Journal of Physiology, EarlyView.
Abstract figure legend The study investigated the modulatory effects of affective touch on temporal summation of second pain (TSSP) in 32 romantic couples (N = 64). The design included a dyadic session (partner's CT‐optimal stroking vs. static touch) and an individual session (robotic CT‐touch vs. vibration control).
Márcia da‐Silva, A. Ribeiro‐Carreira, Mariana Oliveira, Adriana Sampaio, Joana Coutinho, Alberto J. González‐Villar   +5 more
wiley   +1 more source