Results 131 to 140 of about 41,665 (257)

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier   +13 more
wiley   +1 more source

Single human fingertip mechanoreceptive afferents simultaneously encode multidimensional aspects of touch

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mechanoreceptors in the fingertip skin allow us to explore objects and to feel a vast range of textures. We recorded responses from individual low‐threshold mechanoreceptive afferents in humans while dynamic stimuli were swept across their receptive fields, systematically varying force, velocity and spatial period.
Victoria Ashley Lang   +3 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Derivation and analysis of human somatic sensory neuron subtypes facilitated through fluorescent hPSC reporters. [PDF]

open access: yesStem Cell Reports
Malka-Gibor E   +8 more
europepmc   +1 more source

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