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Cellular Basis of Mechanotransduction
The Biological Bulletin, 1998Physical forces, such as those due to gravity are fundamental regulators of tissue development. To influence morphogenesis, mechanical forces must alter growth and function. Yet little is known about how cells convert mechanical signals into a chemical response.
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Mechanotransduction and focal adhesions
Cell Biology International, 2012AbstractCellular FAs (focal adhesions) respond to internal and external mechanical stresses which make them prime candidates for mechanotransduction. Recent observations showed that the FA proteins including vinculin, FAK (FA kinase) and p130Cas are crucial for the ability of cells to transmit forces and to generate cytoskeletal tension.
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Mechanotherapy in oncology: Targeting nuclear mechanics and mechanotransduction
Advanced Drug Delivery Reviews, 2023Jinlu Ma, Guoyou Huang, Tian Jian Lu
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Crosstalk between mechanotransduction and metabolism
Nature Reviews Molecular Cell Biology, 2020Patrizia Romani +2 more
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Cell–extracellular matrix mechanotransduction in 3D
Nature Reviews Molecular Cell Biology, 2023Aashrith Saraswathibhatla +2 more
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Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface
International Journal of Molecular Sciences, 2021Ivan P Uray, Karen Uray
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Balancing forces: architectural control of mechanotransduction
Nature Reviews Molecular Cell Biology, 2011Christopher C Dufort +2 more
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