Results 61 to 70 of about 41,911 (157)
Advanced ScienceIntegrin and focal adhesion can regulate cytoskeleton distribution to govern actin‐related force remodeling and play an important role in nuclear configuration and force‐sensing mechanotransduction of stem cells.
Nana Wang +10 more
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αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish
Biology Open, 2016 Cadherin complexes mediate cell-cell adhesion and are crucial for embryonic development. Besides their structural function, cadherin complexes also transduce tension across the junction-actomyosin axis into proportional biochemical responses.
Mitchell K. L. Han +5 more
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Hic-5 drives epithelial mechanotransduction promoting a feed-forward cycle of bronchoconstriction
Nature CommunicationsMechanical forces are essential for organ function, but excessive or dysregulated forces can promote pathologic conditions. In asthma, bronchoconstriction narrows the airway, compressing the airway epithelium and activating mechanotransduction, yet key ...
Chimwemwe Mwase +10 more
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Under Pressure: Mechanical Stress Management in the Nucleus
Cells, 2016 Cells are constantly adjusting to the mechanical properties of their surroundings, operating a complex mechanochemical feedback, which hinges on mechanotransduction mechanisms.
Néjma Belaadi +2 more
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Experimental PhysiologyAlthough acid‐sensing ion channels (ASICs) are proton‐gated ion channels responsible for sensing tissue acidosis, accumulating evidence has shown that ASICs are also involved in neurosensory mechanotransduction. However, in contrast to Piezo ion channels,
Yi‐Chen Lin +3 more
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Lung Mechanotransduction, the minuet of Biophysics (Part 2)
The dynamic processes associated with lung pathophysiology have always been explored from a traditionalist perspective. This review conceptualizes an amalgam of biological and biophysical concepts that aim to optimize the understanding of the ...
Yolanda López-Fernández +6 more
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Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation
APL BioengineeringMechanotransduction regulates cytoskeletal remodeling, nuclear mechanics, and metabolic adaptation, which are central to cellular aging and rejuvenation.
Hye-Min Han, Su-Yeon Kim, Dong-Hwee Kim
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Toxins, 2019 Bee venom is a mixture of several components with proven therapeutic benefits, among which are anti-inflammatory, analgesic, and various cardiovascular conditions.
Jacinthe Frangieh +6 more
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Mechanotransduction for mesenchymal stem cells
, 2009 107 p.This project is focused on the study of mechanotransduction of Human mesenchymal stem cells (hMSC). A mechanotransduction device was custom made to stimulate mechanotransduction to stem cells by stretching, bending or shearing cultured materials ...
Wu, Shucheng.
core
eLife, 2017 Hair cells of the cochlea are mechanosensors for the perception of sound. Mutations in the LRTOMT gene, which encodes a protein with homology to the catecholamine methyltransferase COMT that is linked to schizophrenia, cause deafness.
Christopher L Cunningham +7 more
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