BioengineeringIn this review, we explore the intricate relationship between glucose metabolism and mechanotransduction pathways, with a specific focus on the role of the Hippo signaling pathway in chondrocyte pathophysiology.
Jacob Jahn +5 more
doaj +1 more source
The Mechanotransduction Signaling Pathways in the Regulation of Osteogenesis
, 2023 Bones are constantly exposed to mechanical forces from both muscles and Earth’s gravity to maintain bone homeostasis by stimulating bone formation.
Chunyan Li +5 more
core +1 more source
Review: Mechanotransduction in ovarian cancer: Shearing into the unknown
APL Bioengineering, 2018 Ovarian cancer remains a deadly diagnosis with an 85% recurrence rate and a 5-year survival rate of only 46%. The poor outlook of this disease has improved little over the past 50 years owing to the lack of early
Caymen Novak, Eric Horst, Geeta Mehta
doaj +1 more source
Osteocyte Mechanotransduction in Orthodontic Tooth Movement
, 2023 Purpose of Review: Orthodontic tooth movement is characterized by periodontal tissue responses to mechanical loading, leading to clinically relevant functional adaptation of jaw bone.
Jianfeng Jin +5 more
core +1 more source
MOLECULES INVOLVED IN THE SPIDER, CUPIENNIUS SALEI, MECHANOTRANSDUCTION
, 2019 The molecular mechanisms involved in mechanical senses such as touch and vibration have been studied for decades using a small number of model preparations in species facilitating genetic manipulation.
Johnson, Jessica
core
The role of DEL1 in chondrocyte expansion and mechanotransduction: an investigative study [PDF]
, 2009 Matrix-induced autologous chondrocyte implantation offers a potential cure for joint disease and is currently challenged by loss of differentiated phenotype upon culture.
Qusous, A.
core +1 more source
Tools to Examine Mechanotransduction
, 2018 Organisms experience acute and chronic mechanical forces. Acute mechanical stimulation in Drosophila induces the ectopic expression of developmental regulatory genes.
Ardon Shorr (4940233)
core +1 more source
A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes [PDF]
European Cells & Materials, 2010 Mechanical forces are translated into biochemical signals and contribute to cell differentiation and phenotype maintenance. Mesenchymal stem cells and their tissue-specific offspring, as osteoblasts and chondrocytes, cells of cardiovascular tissues and ...
W Wilke +14 more
doaj
Lung Mechanotransduction, the minuet of Biophysics (Part 1)
The dynamic processes associated with lung pathophysiology have always been explored from a traditionalist perspective. This review conceptualizes an amalgam of biological and biophysical concepts that aim to optimize the understanding of the ...
Yolanda López-Fernández +6 more
core +1 more source
The interplay between biochemical mediators and mechanotransduction in chondrocytes: Unravelling the differential responses in primary knee osteoarthritis. [PDF]
In primary or idiopathic osteoarthritis (OA), it is unclear which factors trigger the shift of articular chondrocyte activity from pro-anabolic to pro-catabolic.
Segarra-Queralt, Maria +4 more
core +2 more sources