Evaluation and management of patients with early-stage mycosis fungoides who interrupt or discontinue topical mechlorethamine gel because of dermatitis [PDF]
JAAD Case Reports, 2020 Elaine S. Gilmore, MD, PhD +3 more
doaj +3 more sources
Frontiers in Medicine, 2021 Topical chlormethine yields high response rates in mycosis fungoides cutaneous T-cell lymphoma with early discontinuation often attributed to skin reactions.
Christiane Querfeld +5 more
doaj +2 more sources
Mechlorethamine Hydrochloride Gel in the Treatment of Mycosis Fungoides-Type Cutaneous T-Cell Lymphoma (MF-CTCL): A Focus on Patient Selection and Special Considerations. [PDF]
Cancer Manag Res, 2022 Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL) and often has an indolent course, particularly for patients presenting with early-stage (patch/plaque) disease.
Crimp C +3 more
europepmc +4 more sources
Post hoc Analysis of a Randomized, Controlled, Phase 2 Study to Assess Response Rates with Chlormethine/Mechlorethamine Gel in Patients with Stage IA–IIA Mycosis Fungoides [PDF]
Dermatology, 2021 Background: Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Patients can be treated using chlormethine gel, a skin-directed therapy developed and approved for MF.
Christiane Querfeld +8 more
openalex +2 more sources
The PROVe Study: US Real-World Experience with Chlormethine/Mechlorethamine Gel in Combination with Other Therapies for Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma [PDF]
American Journal of Clinical Dermatology, 2021 Chlormethine/mechlorethamine gel is a skin-directed therapy for patients with mycosis fungoides cutaneous T-cell lymphoma. Currently, real-world data on chlormethine gel are lacking.
Ellen J. Kim +8 more
openalex +2 more sources
Drug Design, Development and Therapy, 2018 Kendall Liner,1 Celeste Brown,2 Laura Y McGirt3 1Division of Dermatology, Medical College of Georgia at Augusta Health, Augusta, GA, USA; 2School of Medicine, University of North Carolina at Chapel Hill, Carolinas Medical Center, Charlotte, NC, USA ...
Liner K, Brown C, McGirt LY
doaj +2 more sources
Ointment-based mechlorethamine treatment for mycosis fungoides [PDF]
Cancer, 1983 The treatment of skin disease with topical mechlorethamine has been restricted because of the frequent development of contact dermatitis. A series of 43 patients with mycosis fungoides in Stages 1A (17), IB (22), II (2), and III (2) were treated with an ointment-based mechlorethamine, prepared by an anhydrous method.
Norman M. Price +2 more
openalex +4 more sources
Jak-STAT Inhibition Mediates Romidepsin and Mechlorethamine Synergism in Cutaneous T-Cell Lymphoma
Journal of Investigative Dermatology, 2021 José R. Cortés +12 more
openalex +3 more sources
Evaluating Response Trends of Chlormethine/Mechlorethamine Gel in Patients With Stage I-IIA Mycosis Fungoides: Analysis of Individual Patient Data From a Randomized Controlled Phase II Study to Facilitate Optimal Treatment Experiences [PDF]
Clinical Lymphoma, Myeloma & Leukemia, 2023 Larisa J. Geskin +6 more
openalex +2 more sources