A Retrospective Study of Chemotherapy-Related Extravasation Events in Dogs and Cats. [PDF]
J Vet Intern MedABSTRACT Background Chemotherapy extravasation is a potentially serious complication. There is a paucity of information in the veterinary literature investigating extravasation events, treatments, and outcomes. Objective Evaluate chemotherapy extravasation events and treatments in dogs and cats, adverse events (AEs), and overall outcomes.
Martens E +12 more
europepmc +2 more sources
Experimental bronchial arterial infusion of mechlorethamine
The Journal of Thoracic and Cardiovascular Surgery, 1965 James B.D. Mark +2 more
openaire +4 more sources
Drug Design, Development and Therapy, 2018 Kendall Liner,1 Celeste Brown,2 Laura Y McGirt3 1Division of Dermatology, Medical College of Georgia at Augusta Health, Augusta, GA, USA; 2School of Medicine, University of North Carolina at Chapel Hill, Carolinas Medical Center, Charlotte, NC, USA ...
Liner K, Brown C, McGirt LY
doaj +2 more sources
Ointment-based mechlorethamine treatment for mycosis fungoides [PDF]
Cancer, 1983 The treatment of skin disease with topical mechlorethamine has been restricted because of the frequent development of contact dermatitis. A series of 43 patients with mycosis fungoides in Stages 1A (17), IB (22), II (2), and III (2) were treated with an ointment-based mechlorethamine, prepared by an anhydrous method.
Norman M. Price +2 more
openaire +4 more sources
Jak-STAT Inhibition Mediates Romidepsin and Mechlorethamine Synergism in Cutaneous T-Cell Lymphoma
Journal of Investigative Dermatology, 2021 José R. Cortés +12 more
openalex +3 more sources
Evaluating Response Trends of Chlormethine/Mechlorethamine Gel in Patients With Stage I-IIA Mycosis Fungoides: Analysis of Individual Patient Data From a Randomized Controlled Phase II Study to Facilitate Optimal Treatment Experiences [PDF]
Clinical Lymphoma, Myeloma & Leukemia, 2023 Larisa J. Geskin +6 more
openalex +2 more sources
Cancer Biology & Treatmen, 2021 Mechlorethamine (ME) is an antineoplastic agent which has been in clinical use for more than six decades. ME therapy is associated with high toxicity, and it is often in combination with other therapeutics.
Georgi L. Lukov, Theresa Tuthill
openalex +2 more sources
Sulfur Mustard Analog Mechlorethamine (Bis(2-chloroethyl)methylamine) Modulates Cell Cycle Progression via the DNA Damage Response in Human Lung Epithelial A549 Cells [PDF]
Chemical Research in Toxicology, 2019 Nitrogen mustard, mechlorethamine (bis(2-chloroethyl)methylamine; HN2), and sulfur mustard are potent vesicants that modify and disrupt cellular macromolecules including DNA leading to cytotoxicity and tissue injury.
Yi‐Hua Jan +3 more
openalex +2 more sources
Topical Mechlorethamine for the Treatment of Psoriasis: A Report of Two Cases and Literature Review. [PDF]
Dermatol Ther (Heidelb), 2023 Introduction Psoriasis is a common inflammatory skin disease that significantly impacts patients’ psychosocial wellbeing. Despite increasingly effective treatment options, the recurrence of plaques after discontinuation of therapy in many patients ...
Fahmy LM +4 more
europepmc +2 more sources
Mechlorethamine Hydrochloride Gel [PDF]
Definitions, 2020 A gel formulation composed of the hydrochloride salt form of mechlorethamine, which is a nitrogen mustard alkylating agent and an analog of sulfur mustard, with antineoplastic and immunosuppressive activities. Upon topical application, mechlorethamine is
openalex +2 more sources