Results 41 to 50 of about 3,272 (188)

Necrobiotic Xanthogranuloma Treated With Topical Nitrogen Mustard (Mechlorethamine) [PDF]

open access: bronzeJAMA dermatology, 2016
Necrobiotic Xanthogranuloma Treated With Topical Nitrogen Mustard (Mechlorethamine) Necrobiotic xanthogranuloma (NXG) is a chronic, progressive skin condition characterized by a granulomatous reaction with the potential to affect multiple organs that ...
Olaf Rodriguez   +4 more
openalex   +2 more sources

The Management of Classical Hodgkin's Lymphoma: Past, Present, and Future

open access: yesAdvances in Hematology, 2011
The management of classical Hodgkin's lymphoma (CHL) is a success story of modern multi-agent haemato-oncology. Prior to the middle of the twentieth century CHL was fatal in the majority of cases.
S. E. Richardson, C. McNamara
doaj   +1 more source

Mediastinal Choriocarcinoma Masquerading as Relapsed Hodgkin Lymphoma

open access: yesCase Reports in Oncology, 2011
Primary mediastinal choriocarcinoma is a rare extragonadal germ cell malignancy. We describe the first case of a patient who developed mediastinal choriocarcinoma after treatment for Hodgkin lymphoma (HL).
Selay Lam   +2 more
doaj   +1 more source

Combination of ebselen and hydrocortisone substantially reduces nitrogen mustard-induced cutaneous injury

open access: yesCurrent Research in Toxicology, 2021
The purpose of the present study was to investigate the vesicant countermeasure effects of hydrocortisone (HC) and ebselen (EB-1), administered as monotherapy or as a combination treatment.
Hemanta C Rao Tumu   +2 more
doaj  

Optimizing Care and Compliance for the Treatment of Mycosis Fungoides Cutaneous T-Cell Lymphoma With Mechlorethamine Gel

open access: bronzeClinical Journal of Oncology Nursing, 2015
BACKGROUND Mycosis fungoides is the most common form of cutaneous T-cell lymphoma (MF-CTCL). Quality nursing care is necessary for effective diagnosis and treatment of patients with MF-CTCL. Early-stage MF-CTCL (stages Ia and Ib) is most often managed in
Allister Benjamin Chase   +2 more
openalex   +3 more sources

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens   +3 more
wiley   +1 more source

Mechlorethamine Hydrochloride Gel in the Treatment of Mycosis Fungoides–Type Cutaneous T-Cell Lymphoma (MF-CTCL): A Focus on Patient Selection and Special Considerations

open access: yesCancer Management and Research, 2022
Caitlin Crimp,1 Ameya Gangal,2 Erica S Tarabadkar,3 Michi M Shinohara1,4 1Division of Dermatology, University of Washington, Seattle, WA, USA; 2School of Medicine, Emory University, Atlanta, GA, USA; 3Department of Dermatology, Emory University School of
Crimp C   +3 more
doaj  

Half‐Body Radiation Therapy Results in a Prolonged Progression‐Free Interval in Canine High‐Grade Lymphoma After First Remission

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT An optimal protocol of adding wide‐field irradiation to multi‐agent chemotherapy for dogs with lymphoma has not been established. The aim of this retrospective case–control study was to evaluate the efficacy of a protocol combining chemotherapy and half‐body irradiation (HBI) for dogs with high‐grade lymphoma.
Yen‐Hao Erik Lai   +3 more
wiley   +1 more source

Management of mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL): focus on chlormethine gel

open access: yesCancer Management and Research, 2019
Daphné Denis,1 Nathalie Beneton,1 Kamel Laribi,2 Hervé Maillard1 1Dermatology Department, Centre Hospitalier Le Mans, Le Mans, France; 2Haematology Department, Centre Hospitalier Le Mans, Le Mans, France Abstract: Mycosis fungoides (MF) is ...
Denis D, Beneton N, Laribi K, Maillard H
doaj  

Synthesis and Antiproliferative Activity of Cisplatin‐3–Chloropiperidine Conjugates

open access: yesChemBioChem, Volume 25, Issue 23, December 2, 2024.
Synthesis and characterization of two novel cisplatin‐ alkylating agents conjugates. Combining cisplatin with a sterically demanding cyclic nitrogen mustard. Cytotoxicity of the ligands and the complexes examined with MTT assays. The novel conjugates displayed a high antiproliferative potency against 5 human cancer cell lines.
Mats Georg   +5 more
wiley   +1 more source

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