Results 51 to 60 of about 3,272 (188)
An overview of different methods to establish a murine premature ovarian failure model
Animal Models and Experimental Medicine, Volume 7, Issue 6, Page 835-852, December 2024.Ten different methods to induce murine POF models: (1) POF model induced by chemotherapy drugs, (2) radiotherapy‐induced POF model, (3) genetically induced POF model, (4) POF model induced by D‐galactose, (5) natural ovarian aging (NOA)‐induced POF model (6) physiological POF model with consecutive superovulation, (7) oophorectomy POF model, (8) POF ...
Negar Pouladvand +4 more
wiley +1 more source
Plant‐Based Anticancer Compounds With a Focus on Breast Cancer
Cancer Reports, Volume 7, Issue 10, October 2024.ABSTRACT Breast cancer is a common form of cancer among women characterized by the growth of malignant cells in the breast tissue. The most common treatments for this condition include chemotherapy, surgical intervention, radiation therapy, hormone therapy, and biological therapy.
Amin Moradi Hasan‐Abad +4 more
wiley +1 more source
Cancer Management and Research, 2018 Tingting Zhang,1 Yan Yao,2 Fubin Feng,3 Wenge Zhao,2 Jinhui Tian,4 Chao Zhou,3 Xue Wang,5 Shengjie Dong,6 Jia Li,2 Lingyu Qi,7 Changgang Sun3,8 1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong
Zhang T +10 more
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British Journal of Haematology, Volume 205, Issue 4, Page 1374-1382, October 2024.The therapeutic paradigm in Hodgkin lymphoma has shifted. Study of long‐term cause‐specific mortality in Danish patients show that we cure more patients and see less treatment‐related mortality. Summary The documented treatment‐induced excess mortality in Hodgkin lymphoma (HL) has spurred important treatment changes over recent decades.
Sára Rossetti +12 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2014 Patients with Hodgkin lymphoma treated with DNA-breaking alkylating agents such as mechlorethamine and procarbazine in the MOPP regimen and with topoisomerase II inhibitors, such as etoposide did show a long-term risk of developing therapy-related ...
Ercole Brusamolino +2 more
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Secondary 3‐Chloropiperidines: Powerful Alkylating Agents
ChemistryOpen, Volume 13, Issue 6, June 2024.The synthesis of secondary 3‐chloropiperidines and highly strained bicyclic aziridines is reported, including a new method for the selective mono‐chlorination of unsaturated primary amines. The novel compounds, which closely resemble natural alkylating agents, proved to be more active than previously reported 3‐chloropiperidines in a DNA cleavage assay,
Mats Georg +5 more
wiley +1 more source
Journal of feline medicine and surgery, 2017 Objectives The goals of this retrospective study were to evaluate the use of mechlorethamine, vincristine, melphalan and prednisolone (MOMP) chemotherapy for rescue of feline lymphoma, to describe the protocol’s toxicity and to determine prognostic ...
O. Martin, J. Price
semanticscholar +1 more source
Insights on cyclophosphamide metabolism and anticancer mechanism of action: A computational study
Journal of Computational Chemistry, Volume 45, Issue 10, Page 663-670, April 15, 2024.The outcomes of a density functional theory (DFT) computational mechanistic study of the main cyclophosphamide (CP) activation steps leading to the formation of the active phosphoramide mustard form and the DNA alkylating action of this latter are illustrated.
Eslam Dabbish +6 more
wiley +1 more source
Arabian Journal of Chemistry, 2019 Based on the heterocyclic core of bendamustine, four series (4a–g, 5a–f, 8a–b and 9a–b) of benzimidazole derivatives were designed and synthesized starting from 4-(1H-benzo[d]imidazol-2-yl)-4-oxobutanehydrazide. In the rational design of target molecules,
Mohd Rashid +9 more
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