Results 31 to 40 of about 13,809 (280)

Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signalling in the mouse hypothalamus

Frontiers in Neuroscience, 2013
In the mouse hypothalamus, ciliary neurotrophic factor (CNTF) is mainly expressed by ependymal cells and tanycytes of the ependymal layer covering the third ventricle.
Ilenia eSeveri, Jessica ePerugini, Eleonora eMondini, Arianna eSmorlesi, Andrea eFrontini, Saverio eCinti, Saverio eCinti, Antonio eGiordano   +7 more
doaj   +1 more source

Ultrastructure of Hypothalamic Neurons and of the Median Eminence [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1974
SUMMARYOur light, and electron microscopic (EM) findings within the hypothalamic supraoptic (SO) and paraventricular (PV) nuclei of the normal female rabbit are in agreement with those reported earlier by other investigators for the same nuclei of the dog and rat.
openaire   +2 more sources

Effect of maternal deprivation on the gonadotrophin-releasing hormone (GnRH) and GnRH-associated peptide neurobiology in lambs during the transition from infancy to prepuberty.

Folia Histochemica et Cytobiologica, 2010
Using morphological criteria we describe the effect of maternal deprivation on the gonadotrophin-releasing hormone (GnRH) and GnRH-associated peptide (GAP) of the GnRH prohormone (proGnRH) in the preoptic area (POA)-hypothalamus during the weaning period.
Jolanta Polkowska, Marta Wańkowska
doaj   +1 more source

Arthroscopic tri-pulley Technology reduction and internal fixation of pediatric Tibial Eminence fracture: a retrospective analysis

BMC Musculoskeletal Disorders, 2020
Background Fixing a tibial eminence fracture with a tri-pulley is a new technique. The purpose of this study was to present the early clinical outcome of arthroscopic tri-pulley suture fixation for tibial eminence fractures in children.
Liang Zhang, Li Zhang, Jiang Zheng, Bo Ren, Xin Kang, Xian Zhang, Xiaoqian Dang   +6 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus

Frontiers in Cellular Neuroscience, 2020
In humans and experimental animals, the administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight. To gain further insights into the mechanism(s) underlying its satiety effect, we: (i) evaluated the CNTF-dependent ...
Wiebe Venema, Ilenia Severi, Jessica Perugini, Eleonora Di Mercurio, Marco Mainardi, Margherita Maffei, Saverio Cinti, Saverio Cinti, Antonio Giordano   +8 more
doaj   +1 more source

Netrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner. [PDF]

PLoS ONE, 2012
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are required for fertility in all mammalian species studied to date. In rodents, GnRH neuron cell bodies reside in the rostral hypothalamus, and most extend a single long neuronal process in the ...
Victoria F Low, Zeno Fiorini, Lorryn Fisher, Christine L Jasoni   +3 more
doaj   +1 more source

Role of catecholamines in regulating ovine median eminence blood flow

, 1990
Blood flow was measured in the ovine median eminence and neural lobe before and after the intravenous infusion of dopamine (n = 7), the D1 agonist SKF 38393 (n = 4), the D2 agonist bromocriptine (n = 4), and the dopamine antagonist haloperidol (n = 5 ...
J. Townsend, R. B. Page, R. M. Bryan, S. Davis, M. Gropper, E. Woodard   +5 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Protocol for targeting the magnocellular neuroendocrine cell ensemble via retrograde tracing from the posterior pituitary

STAR Protocols, 2021
Summary: The hypothalamic magnocellular neuroendocrine cells (MNCs) project to the posterior pituitary (PPi), regulating reproduction and fluid homeostasis.
Bin Zhang, Liyao Qiu, Chaoying Long, Zhihua Gao   +3 more
doaj   +1 more source