Results 1 to 10 of about 5,447 (154)
VWA3A-Derived Ependyma Promoter Drives Increased Therapeutic Protein Secretion Into the CSF
Molecular Therapy - Nucleic Acids, 2023 Recombinant adeno-associated viral vectors (rAAVs) are a promising strategy to treat neurodegenerative diseases because of their ability to infect non-dividing cells and confer long-term transgene expression.
Beverly L. Davidson +2 more
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Biomolecules, 2023 The neuron loss caused by the progressive damage to the nervous system is proposed to be the main pathogenesis of neurodegenerative diseases. Ependyma is a layer of ciliated ependymal cells that participates in the formation of the brain-cerebrospinal ...
Feng Qian, Lian Liu, Feng Ru Tang
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The Fine Structure of Ependyma in the Brain of the Rat [PDF]
Journal of Cell Biology, 1963 The ciliated ependyma of the rat brain consists of a sheet of epithelial cells, the luminal surface of which is reflected over ciliary shafts and numerous evaginations of irregular dimensions. The relatively straight lateral portions of the plasmalemma of contiguous cells are fused at discrete sites to form five-layered junctions or zonulae occludentes
S L Palay, M W Brightman
exaly +3 more sources
CXCR4 and CXCR6 dually limit T cell entry into the polyomavirus-infected brain [PDF]
Journal of NeuroinflammationT cell responses are vital for controlling viral infection in the central nervous system (CNS), but must be tightly regulated to limit tissue-damaging inflammation.
Kalynn M. Alexander +8 more
doaj +2 more sources
Constitution of the Ependyma in the Chicken Telencephalon
Journal of Veterinary Medical Science, 2011 The constitution of ependyma derived from the ventricular zone is different from that derived from other regions of the central nervous system. In the mammalian cerebrum, the ependyma is varied by the regions to cortex or basal ganglia (BG). In the avian telencephalon (Tc), previous studies about the constitution of the ependyma have not revealed clear
Yoshinao Z Hosaka +2 more
exaly +4 more sources
History of Research Concerning the Ependyma: A View From Inside the Human Brain
Frontiers in Cellular NeuroscienceThe history of research concerning ependymal cells is reviewed. Cilia were identified along the surface of the cerebral ventricles c1835. Numerous anatomical and histopathological studies in the late 1800’s showed irregularities in the ependymal surface ...
Del Bigio Marc R
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Heterogeneity of the adult mammalian forebrain neurogenic ependyma: A comprehensive cellular map [PDF]
Neural Regeneration ResearchThe presence or absence of adult neural stem cells in the mammalian forebrain ependyma has been debated for two decades. In this study, we performed single-cell RNA sequencing to investigate the cellular composition of the ependymal surface of the adult ...
Xuejiao Yang +7 more
doaj +2 more sources
Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus [PDF]
Fluids and Barriers of the CNSAQP4 is expressed in the endfeet membranes of subpial and perivascular astrocytes and in the ependymal cells that line the ventricular system. The sporadic appearance of obstructive congenital hydrocephalus (OCHC) has been observed in the offspring of ...
Francisco Mayo +8 more
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Regional Differences of Proliferation Activity in the Spinal Cord Ependyma of Adult Rats
Open Life Sciences, 2012 Enikő Račeková +2 more
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Frontiers in Neuroscience, 2023 The epithelium covering the surfaces of the cerebral ventricular system is known as the ependyma, and is essential for maintaining the physical and functional integrity of the central nervous system.
Patricia Paez-Gonzalez +7 more
doaj +1 more source