Results 21 to 30 of about 7,972 (202)

Single Cell Transcriptomics of Ependymal Cells Across Age, Region and Species Reveals Cilia-Related and Metal Ion Regulatory Roles as Major Conserved Ependymal Cell Functions

Frontiers in Cellular Neuroscience, 2021
Ependymal cells are ciliated-epithelial glial cells that develop from radial glia along the surface of the ventricles of the brain and the spinal canal.
Adam MacDonald, Brianna Lu, Maxime Caron, Nina Caporicci-Dinucci, Dale Hatrock, Kevin Petrecca, Guillaume Bourque, Jo Anne Stratton   +7 more
doaj   +1 more source

Quantifying cilia beat frequency using high‐speed video microscopy: Assessing frame rate requirements when imaging different ciliated tissues

Physiological Reports, 2022
Motile cilia are found in numerous locations throughout our body and play a critical role in various physiological processes. The most commonly used method to assess cilia motility is to quantify cilia beat frequency (CBF) via video microscopy.
Luke Scopulovic, Deanne Francis, Elvis Pandzic, Richard Francis   +3 more
doaj   +1 more source

The Ependymal Region Prevents Glioblastoma From Penetrating Into the Ventricle via a Nonmechanical Force

Frontiers in Neuroanatomy, 2021
BackgroundIntraventricular penetration is rare in glioblastoma (GBM). Whether the ependymal region including the ependyma and subventricular zone (SVZ) can prevent GBM invasion remains unclear.MethodsMagnetic resonance imaging (MRI) and haematoxylin ...
Kaishu Li, Kaishu Li, Haimin Song, Chaohu Wang, Zhiying Lin, Guozhong Yi, Runwei Yang, Bowen Ni, Ziyu Wang, Taichen Zhu, Wanghao Zhang, Xiran Wang, Zhifeng Liu, Guanglong Huang, Yawei Liu, Yawei Liu   +15 more
doaj   +1 more source

Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus

Nature Communications, 2018
Specialized, differentiated cells often perform unique tasks that require them to maintain a stable phenotype. Multiciliated ependymal cells (ECs) are unique glial cells lining the brain ventricles, important for cerebral spinal fluid circulation.
Khadar M. Abdi, Chun‐Hsiang Lai, Patricia Páez-González, Mark Lay, Joon Pyun, C. Kuo   +5 more
semanticscholar   +1 more source

Molecular characterization of rabbit phospholipid transfer protein: choroid plexus and ependyma synthesize high levels of phospholipid transfer protein

Journal of Lipid Research, 2002
Phospholipid transfer protein (PLTP) plays an important role in plasma lipoprotein metabolism. However, PLTP is expressed in a wide range of tissues suggesting additional local functions.
Roland Gander, Philipp Eller, Susanne Kaser, Igor Theurl, Doris Walter, Teresa Sauper, Andreas Ritsch, Josef R. Patsch, Bernhard Föger   +8 more
doaj   +1 more source

Ependymal cells SCOre sweet cerebrospinal fluid.

PLoS Biology, 2023
The subcommissural organ (SCO) is a secretory tissue located on the roof of the brain's third ventricle. A new study published in PLOS Biology finds that the SCO responds to glucose by secreting signaling molecules into the cerebrospinal fluid (CSF ...
Luke L Liu, Ryann M Fame
doaj   +1 more source

Intraventricular dysembryoplastic neuroepithelial tumor in the temporal horn with Broad involvement of the ependyma

Clinical Case Reports, 2021
Key Clinical Message Though typical dysembryoplastic neuroepithelial tumors (DNETs) are located in the cerebral cortex, an atypical DNET could occur in the temporal horn of the lateral ventricle and broadly involve the ependyma.
Luying Li, Xiao Hu, Jingmei Li, Heng Zhang   +3 more
doaj   +1 more source

Neogenin Recruitment of the WAVE Regulatory Complex to Ependymal and Radial Progenitor Adherens Junctions Prevents Hydrocephalus

Cell Reports, 2017
Denudation of the ependyma due to loss of cell adhesion mediated by cadherin-based adherens junctions is a common feature of perinatal hydrocephalus. Junctional stability depends on the interaction between cadherins and the actin cytoskeleton.
Conor J. O’Leary, Cathrin C. Nourse, Natalie K. Lee, Amanda White, Michael Langford, Kai Sempert, Stacey J. Cole, Helen M. Cooper   +7 more
doaj   +1 more source

Cerebral sparganosis in a child with corpus callosum invasion: a case report

BMC Infectious Diseases, 2023
Background Invasion of the corpus callosum by sparganosis is rare in children. After invading the corpus callosum, sparganosis has various migration modes, which can break through the ependyma and enter the ventricles, thus causing secondary migratory ...
Xiwen Chen, Huiying Wu, Lianwei Lu, Ning Zhou, Zhen Chen, Xiaochun Zhang   +5 more
doaj   +1 more source

Prenatal Events and CNS Migration Disorders

Pediatric Neurology Briefs, 1994
The role of pre-, peri-, and postnatal environmental factors and genetic predisposition in the genesis of neuronal migration disorders (NMD) in 40 patients with epilepsy was determined by standardized questionnaires at the Montreal Neurological Institute
J Gordon Millichap
doaj   +1 more source