Results 241 to 250 of about 711,203 (301)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Correction: The influence of parental educational expectations on primary school students' social-emotional competence: the chain mediation effect of peer relationships and academic self-efficacy. [PDF]

Front Psychol
Yang L, Chen K, Ma S, Lei Y.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Letter to the editor: "Mediation effect of healthy lifestyles on the association of socioeconomic status with mortality among US cancer survivors: a population-based cohort study". [PDF]

Int J Surg
Shi X, Zhang P.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

How Does Subjective Social Status Associate With Depression Among the Labor Force Population in China? - Analysis of the Mediation Effect Based on the Sense of Social Equity. [PDF]

Int J Public Health
Zhang H, Ren X, Zhou Y.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The mediation effect of sleep quality on the association between ambient air pollution and type 2 diabetes among UK adults: a population-based cohort study. [PDF]

BMC Public Health
Lin Y, Gao Y, Wang J, Ye S, Luo Z, Huang N, Xiao F.   +6 more
europepmc   +1 more source

Chain-mediation effect of cognitive flexibility and depression on the relationship between physical activity and insomnia in adolescents. [PDF]

BMC Psychol
Yi Z, Wei L, Xu L, Pang W, Liu Y.
europepmc   +1 more source

The effects of learning experience on college students' deep english learning: a study of the chain mediation effect of motivation and strategy. [PDF]

PLoS One
Zhang Q, Jin H, Teng WW.
europepmc   +1 more source