Results 101 to 110 of about 7,354,871 (298)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Study of CA-125 and VEGF biomarkers in drained peritoneal solution in peritoneal dialysis patients
, 2023 Introduction:During long-term treatment with peritoneal dialysis, structural and functional changes occur in the peritoneal membrane (PM). Peritoneal biopsy is the gold standard for detecting histopathological changes in the peritoneum, but as an ...
Borisova, Darina; Medical University of Varna
core +2 more sources
THE UNIVERSITY OF DURHAM AND THE MEDICAL CURRICULUM. [PDF]
The Lancet, 1902 n ...
openaire +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Erbium lasers in periodontology
, 2017 There are many advantages to using lasers in periodontal therapy, including better visualization of cutting, patient acceptance, and detoxification of a periodontal pocket.
Hristov, Ivailo; Medical University of Varna +3 more
core +2 more sources
Evaluation Of Healthcare Services Of Medical Universities\' Websites In Line With E-Government
پیاورد سلامت, 2014 Background and Aim: Due to the role of websites in delivering e-services, this study aims to benchmark rendering healthcare services at medical universities' websites based on Chandler and Emanuel’s four-stage e-government maturity model.
Mehrdad Farzandipour +2 more
doaj
RUDN Journal of Informatization in EducationProblem statement . The dissonance between the pace of technological advancement in clinical practice and the relative stasis of traditional medical pedagogy represents a critical challenge.
Kristina S. Itinson
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source