Results 121 to 130 of about 7,354,871 (298)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Distance learning - a new era of the medical education

, 2010
Recently, the number of distance learning programs offered by several American and European universities substantially in creases. A lot of conventional universities are currently involved in postgraduate distance learning provision, with new courses ...
Ignatov, Valentin; Medical University of Varna, Tonev, Anton; Medical University of Varna, Kolev, Nikola; Medical University of Varna, Ivanov, Krasimir; Medical University of Varna   +3 more
core   +1 more source

Current methods active learning of postgraduate students

Journal of Education, Health and Sport, 2017
In the article the experience ofOdessaNationalMedicalUniversityon providing practical training at postgraduate level study. Defined organizational and methodological aspects of the given type of training are implemented complex measures to improve its ...
O. P. Rogachevskiy, L. M. Popova, N. M. Rozhkovska, O. M. Stepanovichus, M. Y. Golubenko   +4 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Enteric nervous system – a historical review and contemporary aspects

The Enteric Nervous System (ENS) was described over a century ago and has since sparked controversy in scientific circles and the periodical press. Over time, knowledge about the structure, functions, and clinical significance of the ENS has evolved. The
Pavlov, Pavel; Varna Medical University
core   +2 more sources

Documentary analysis and assessment of the curriculum in Bulgarian faculties of pharmacy

, 2016
Introduction“Pharmacist” is one of the regulated professions, which is covered in Directive 2005/36/EC, amended by Directive 2013/55/EC, which means that access to and practice of it demands for a specific professional qualification and competences. Thus,
Dimova, Galina; Medical University of Varna, Getov, Ilko; Medical University of Sofia, Grigorov, Evgeni; Medical University of Varna   +2 more
core   +1 more source

Notice of Duplicate Publication; Perceived benefits of pre-clinical simulation-based training on clinical learning outcomes among Omani undergraduate nursing students

Sultan Qaboos University Medical Journal, 2015
Sultan Qaboos University Medical Journal
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source