Results 131 to 140 of about 7,354,871 (298)

Dynamic change of NT- PROBNP in patients with ST-elevation myocardial infarction treated with primary coronary intervention

open access: yes, 2016
In the recent years important biomarkers have  emerged as  tools for diagnosis and risk stratification in cardiovascular diseases. Such markers are B- type natriuretic peptide ( BNP) and N- terminal B- type  natriuretic peptide (NT-proBNP).Peripheral ...
Valkov, Veselin Dobrev; Medical University of Varna   +10 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Propuesta de indicadores para la acreditación de secretarías generales en los centros de educación médica superior Proposed indicators for the accreditation of general secretariats in higher medical education centers

open access: yesMedisan, 2011
Se conformaron 4 sistemas de indicadores cualitativos: infraestructura, servicio brindado, satisfacción del usuario y satisfacción del colaborador, que permitan acreditar las secretarías generales de las universidades de ciencias médicas, pues la nueva ...
Liliana Leyva Rosales
doaj  

Mentoring within the federal innovation platform System of Personalized Training in a Higher Education Establishment

open access: yesКардиоваскулярная терапия и профилактика
Aim. The article is devoted to the analysis of personalized training through the lens of the mentoring system at a medical university.Material and methods.
A. I. Artyukhina   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

El aprendizaje desde la perspectiva de la motivación profesional y las actitudes Learning from the perspective of the professional motivation and attitudes

open access: yesMedisan, 2011
Se revisan y analizan los elementos teóricos inherentes a la motivación en general y la profesional en particular, con vista a determinar la implicación de esta última en el rendimiento académico de los estudiantes de medicina, a la vez que se profundiza
Guillermo Vallejo Portuondo
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Medical University of South Carolina Sustainability and Resilience

open access: yes
This PowerPoint presentation discusses strategic energy management, resilience, and emergency preparedness at the Medical University of South ...
Medical University of South Carolina   +1 more
core  

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