Results 91 to 100 of about 4,310 (188)

Factors affecting the efficacy of nonsurgical therapy of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Objectives and Materials and Methods This article critically reviews the current knowledge on the factors influencing the efficacy of non‐surgical therapy (NST) of peri‐implantitis, taking also advantage of the know‐how from periodontitis management.
Elena Calciolari, Federico Rivara, Nikolaos Donos, Jérôme F. Lasserre, Selena Toma   +4 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Denosumab-related osteonecrosis of the external auditory canal—benefit of the early surgical management

Ear, Nose & Throat Journal
Background: Antiresorptive drugs are widely used to reduce bone mineral loss in patients with osteoporosis and to prevent skeletal-related events in patients with metastatic cancers and multiple myeloma (MM).
Vojtěch Peřina PhD, Richard Salzman PhD, Jana Treglerová MD   +2 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 139-149, July 2026.
We compared the initial efficacy of denosumab (Dmab) and zoledronate (ZOL) in treatment‐naive patients with osteoporosis. This cohort study, based on TriNetX data, evaluated the risks of fractures and mortality using Kaplan–Meier survival analyses, with hazard ratios (HRs) and 95% confidence intervals (CIs).
Ko‐Hsiu Lu, Shiow‐Ing Wang, Shun‐Fa Yang   +2 more
wiley   +1 more source

Oxypaeoniflorin Ameliorates Titanium Particle‐Stimulated Osteolysis by Targeting Nrf2 to Reprogram Mitochondrial Homeostasis in Osteoclasts

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Wear debris surrounding implants plays a crucial role in the development of periprosthetic osteolysis (PPO) by inducing the aggregation of osteoclasts around the prosthesis. Oxypaeoniflorin (OPF), a derivative of Paeoniflorin, is primarily sourced from the root of the traditional Chinese medicine peony and possesses anti‐inflammatory and ...
Feng Zhu, Zebin Wu, Jinxuan Hei, Huaqiang Tao, Wenming Li, Kai Chen, Qihan Wang, Dechun Geng, Zhidong Wang, Yaozeng Xu, Shujun Lv   +10 more
wiley   +1 more source

Evaluation of medication-related osteonecrosis of the jaw using the Japanese Adverse Drug Event Report database

Therapeutics and Clinical Risk Management, 2018
Ayaka Inada, Keiko Hosohata, Saki Oyama, Iku Niinomi, Yasuhiro Mori, Yuki Yamaguchi, Mayako Uchida, Kazunori Iwanaga Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, Takatsuki, Osaka 569-1094, Japan ...
Inada A, Hosohata K, Oyama S, Niinomi I, Mori Y, Yamaguchi Y, Uchida M, Iwanaga K   +7 more
doaj  

How we manage medication-related osteonecrosis of the jaw

European Journal of Medical Research
Bone-modifying agents (BMAs) are integral to managing patients with advanced cancer. They improve quality of survival by reducing skeletal-related events, treating hypercalcaemia and chemotherapy-induced bone loss (Coleman in Clin Cancer Res 12: 6243s ...
H. Byrne, S. O’Reilly, C. S. Weadick, P. Brady, R. Ni Ríordáin   +4 more
doaj   +1 more source

Surgical extraction with photobiomodulation as an adjunctive modality in patients at-risk for medication-related osteonecrosis of the jaw: retrospective study

BMC Oral Health
Aim The study aims to retrospectively assess and share the experience of the use of photobiomodulation (PBM) as an adjunctive to surgical extraction in patients at-risk for medication-related osteonecrosis of the jaw (MRONJ) due to a treatment history ...
Gianluca Tenore, Ahmed Mohsen, Alessandro Del Vecchio, Gaspare Palaia, Federica Rocchetti, Lucia Borghetti, Giuseppe Vasile, Francesca Graniero, Umberto Romeo   +8 more
doaj   +1 more source

Non-Surgical Therapy For Denosumab-Associated Jaw Osteonecrosis: Case Report

International Dental Journal
Introduction: This case report describes non-surgical management of denosumab-related osteonecrosis of the jaw to inform treatment strategies for medication-related osteonecrosis of the jaw (MRONJ) in patients with systemic comorbidities.
Junyan Gao, Chunxu Lv
doaj   +1 more source