Results 71 to 80 of about 178,848,266 (217)
Oral Diseases, EarlyView.ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis +6 more
wiley +1 more source
Iatrogenic risk of osteonecrosis of the jaw? Bone substitutes for dental implants: a warning from Japan [PDF]
, 2020 2020-02Commercial bone substitutes that are widely used for bone augmentation for dental implants are predisposing factors in the development of osteonecrosis of the jaw (ONJ), overlooking this situation may lead to serious problems.
Hibi, Hideharu
core +1 more source
Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw
Oral Diseases, EarlyView.ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park +5 more
wiley +1 more source
Journal of Oral Medicine and Oral SurgeryPatients often request oral rehabilitation after surgical resection. Here, a 19-year-old patient developed medication-related osteonecrosis of the jaw after treatment with antiresorptive therapy.
Salabert Noémie +3 more
doaj +1 more source
Interventions for managing medication-related osteonecrosis of the jaw [PDF]
Cochrane Database of Systematic Reviews, 2017 Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and involves the progressive destruction of bone in the mandible or maxilla.
Natalie H, Beth-Tasdogan +3 more
openaire +2 more sources
Oral Health Screening Prior to Oncological Treatment—The Helsinki Protocol
Oral Diseases, EarlyView.ABSTRACT Objectives Oncological treatments can have adverse effects on oral health and cause long‐term complications such as osteonecrosis. This retrospective study investigated the oral health of head and neck cancer patients before radiotherapy and patients with multiple myeloma, breast, prostate, lung, and kidney cancers before antiresorptive ...
Jemina Järvinen +4 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objectives To determine whether pretreatment radiomics can predict medication‐related osteonecrosis of the jaw (MRONJ). Methods Patients with mandibular MRONJ at Hiroshima University Hospital (2009–2024) who underwent MDCT before initiating bone resorption inhibitors were retrospectively identified. Records from 2009 to 2020 were also reviewed
Masaru Konishi
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective To investigate the effects of sequential administration of romosozumab and denosumab on post‐extraction socket healing and osteonecrosis development in a murine tooth extraction model. Methods Forty female mice were randomly assigned to four groups: control (Ctrl), romosozumab (Rm), denosumab (Dmab), and sequential romosozumab ...
Seo‐Yeong An +3 more
wiley +1 more source
Ibrutinib-associated osteonecrosis of the jaw
Oral Oncology ReportsIbrutinib is an FDA-approved first-generation oral Bruton tyrosine kinase (BTK) inhibitor that has been used in the treatment of patients with chronic lymphocytic leukemia (CLL).
Annu Singh +5 more
doaj +1 more source
Oral Surgery, EarlyView.ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra +3 more
wiley +1 more source