Results 71 to 80 of about 4,310 (188)

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Osteoclast-Derived Exosomes Promote The Occurrence And Development Of MRONJ

International Dental Journal
Aim or purpose: The treatment and prevention of medication-related osteonecrosis of the jaw (MRONJ) is a challenge. It is crucial to study the mechanism of MRONJ to carry out precise prevention and treatment.
Kun Zhang, Zhang Jiankang, Pan Jian
doaj   +1 more source

The Role of the Mylohyoid Line in the Spread of Mandibular Odontogenic Deep Neck Infection

Oral Diseases, EarlyView.
ABSTRACT Introduction Although mandibular odontogenic deep neck infections are occasionally fatal, the transmission pathway has not been elucidated. Materials and Methods This multicenter retrospective study was comprised of the patients of both sexes who were over 18 years of age and who had mandibular odontogenic deep neck abscesses.
Eiji Iwata, Kyoichi Obata, Shogo Kikuta, Naoki Kaneko, Kotaro Sato, Norio Kitagawa, Yohei Takeshita, Katsuhisa Matsuo, Junsei Sameshima, Akira Tachibana, Shintaro Kawano, Jingo Kusukawa, Masaya Akashi, Soichiro Ibaragi, Joe Iwanaga   +14 more
wiley   +1 more source

Potential relationship among CT and MRI imaging, histological findings, and treatment outcomes in patients with medication-related osteonecrosis of the jaw undergoing segmental mandibulectomy–A retrospectives study

Journal of Dental Sciences
Background/purpose: Surgical treatment has recently been recommended as a standard therapy for medication-related osteonecrosis of the jaw (MRONJ). However, no established methods exist for determining the extent of bone resection.
Mizuho Ohnuma, Masahiro Umeda, Keisuke Omori, Kei-ichiro Miura, Yuki Sakamoto, Mitsunobu Otsuru, Tomohiro Yamada   +6 more
doaj   +1 more source

Medication‐related osteonecrosis of the jaws caused lethal sepsis in an edentulous patient with multiple systemic factors

Clinical Case Reports, 2017
Key Clinical Message Medication‐related osteonecrosis of the jaw (MRONJ) is developed even in the patients who are edentulous and treated with short‐term bisphosphonate therapy and oral administration.
Keisuke Yamashiro, Aki Sato, Fumihiko Okazaki, Makoto Nakano, Koichi Sawaki, Yasuhisa Hirata, Eiki Yamachika, Seiji Iida, Shogo Takashiba   +8 more
doaj   +1 more source

Is Fluorescence‐Guided Surgery Reliable for the Treatment of MRONJ? A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis, Alessandro Donato Tescione, Ivan Michele Aniceto, Cosimo Rupe, Gioele Gioco, Romeo Patini, Carlo Lajolo   +6 more
wiley   +1 more source

Medication-Related Osteonecrosis of the Jaw (MRONJ) [PDF]

Journal of Oral and Maxillofacial Surgery, 2021
openaire   +2 more sources

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Oral Health Screening Prior to Oncological Treatment—The Helsinki Protocol

Oral Diseases, EarlyView.
ABSTRACT Objectives Oncological treatments can have adverse effects on oral health and cause long‐term complications such as osteonecrosis. This retrospective study investigated the oral health of head and neck cancer patients before radiotherapy and patients with multiple myeloma, breast, prostate, lung, and kidney cancers before antiresorptive ...
Jemina Järvinen, Johanna Uittamo, Hanna Välimaa, Tero Puolakkainen, Aleksi Haapanen   +4 more
wiley   +1 more source

Radiomics Analysis for Predicting Medication‐Related Osteonecrosis of the Jaw Using Computed Tomography

Oral Diseases, EarlyView.
ABSTRACT Objectives To determine whether pretreatment radiomics can predict medication‐related osteonecrosis of the jaw (MRONJ). Methods Patients with mandibular MRONJ at Hiroshima University Hospital (2009–2024) who underwent MDCT before initiating bone resorption inhibitors were retrospectively identified. Records from 2009 to 2020 were also reviewed
Masaru Konishi
wiley   +1 more source