Results 51 to 60 of about 4,310 (188)

Medication-Related Osteonecrosis of Jaw

ANNAL OF STOMATOLOGY
Medication-related osteonecrosis of the jaws (MRONJ) primarily occurs as a complication of bone antiresorptive treatment in specific bone treatment modalities. It was first identified in 2003 as a bisphosphonate (BP) treatment complication. Denosumab is a molecule with a particular mode of action.
Yue He, Hui Shan Ong, Zhen Tian, Lin Zhu, Hang Chen   +4 more
openaire   +2 more sources

The Role Of Hmgb1-Related Inflammation Signals In Bronj

International Dental Journal
Aim or purpose: BRONJ causes prolonged inflammation, resulting in delayed wound healing. High mobility group box-1 (HMGB1) is secreted into the extracellular milieu in response to stimuli, which mediates various inflammatory diseases and affects wound ...
Li Shurong, Yan Jiayi
doaj   +1 more source

Staging in Gerodontology: A Framework

Gerodontology, EarlyView.
ABSTRACT Introduction Comprehensively, systematically and reproducibly assessing and describing the (oral) health status and care needs of older adults is challenging. We aimed to provide a framework for evaluating and reporting older adults' oral health, capturing general and oral function and disease, as well as oral, systemic and socio‐economic ...
Falk Schwendicke, Gerry McKenna, Murali Srinivasan, Azize Bell, Najla Chebib, Cristiane Da Mata, Helena Dujic, Jennifer Gallagher, Barbara Janssens, Danielle M. Layton, Manabu Kanazawa, Anastassia Kossioni, Sabrina Maniewicz, Koichiro Matsuo, Pedro Molinero Mourelle, Annika Neri, Takahiro Ono, Sungkrit Pojmonpiti, Foteini Spyraki, Kittipit Srisanoi, Saif S. Syed, Sayaka Tada, Georgios Tsakos, Terry R. Walton, W. Murray Thomson, Jean‐Philippe Haesler, Sophie Dartevelle, Frauke Müller   +27 more
wiley   +1 more source

Multiple External Invasive Root Resorption and Calcification in Systemic Sclerosis—Case Report

International Endodontic Journal, EarlyView.
ABSTRACT Aim There are few reports in the literature of multiple external invasive root resorption (EIRR) lesions in patients with systemic sclerosis (SSc), and an association between root resorption and SSc is not well established. We report the only case that comprehensively illustrates—with the combination of histopathology, cone beam computed ...
Jee‐Yun Leung, Geoffrey Heithersay, Richard Logan, Sharon Liberali   +3 more
wiley   +1 more source

Medication-related osteonecrosis of the jaw in a patient with multiple myeloma

Journal of Indian Academy of Oral Medicine and Radiology, 2015
Osteonecrosis of jaws is a common complication of parenteral nitrogen-containing bisphosphonates and recently medication-related osteonecrosis of the jaw (MRONJ) is contributing to the growing number of similar osteonecrosis cases which involve maxilla ...
Nupur Bhardwaj, Mariappan Jonathan Daniel, Subramanian Vasudevan Srinivasan, Vannathan Kumaran Jimsha   +3 more
doaj   +1 more source

Denosumab discontinuation and fracture risk: getting the balance right

Internal Medicine Journal, EarlyView.
Abstract Denosumab is a highly effective therapy for osteoporosis. Since its approval by the Therapeutic Goods Administration (TGA) in 2010, use of denosumab has surged across Australia, delivering substantial fracture‐prevention benefits to tens of thousands of patients. However, stopping denosumab may lead to acute loss of bone with an increased risk
Albert S. Kim, Christian M. Girgis
wiley   +1 more source

Medication-related osteonecrosis of the jaw. Introduction of a new modified experimental model [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE : To evaluate a modified experimental model for medication-related osteonecrosis of the jaw (MRONJ) through the upper right central incisor extraction followed by intravenous bisphosphonate administration. METHODS: Forty five rats underwent the
Cláudia Curra, Camila Lopes Cardoso, Osny Ferreira Júnior, Marcos Martins Curi, Mariza Akemi Matsumoto, Bruno Cavalini Cavenago, Pâmela Letícia dos Santos, Joel Ferreira Santiago Júnior   +7 more
doaj   +1 more source

Medication‐related osteonecrosis of the jaw – a current review [PDF]

Oral Surgery, 2018
AbstractAimThis study was aimed to discuss different classes of antiresorptive agents and their modes of action, to review the proposed mechanisms in the pathophysiology of osteonecrosis development and to analyse the prevention and the management of medication‐related osteonecrosis of the jaw.Materials and methodsThree databases were searched for ...
F. Domah, N. Shah, J. Domah, R. Shah
openaire   +1 more source

Assessing the ability of large language models to summarize and generate maxillofacial prosthetic treatment options

Journal of Prosthodontics, EarlyView.
Abstract Purpose The aim was to evaluate the ability of four large language models (LLMs) (OpenAI's ChatGPT‐3.5, Microsoft 365 Copilot, DeepSeek‐R1, and Google Gemini 2.5 Pro) to develop treatment options when presented with clinical cases published in the maxillofacial prosthodontics literature.
Leila M. Sears, Merve Koseoglu, Stavroula Antonopoulou, Sarah Kay Youny Lee, Michael Kase, Amanda Colebeck, Yu‐Chun (Jessie) Lin, Heidi Huber, Maribeth Krzesinski, Alvin G. Wee, Cortino Sukotjo   +10 more
wiley   +1 more source

Comparative survival analysis of endodontic re‐treatment and single‐tooth implants: A retrospective cohort study using shared frailty modeling

Journal of Prosthodontics, EarlyView.
Abstract Purpose To compare the long‐term survival of nonsurgical endodontic re‐treatment versus single‐tooth implants and to identify independent demographic, systemic, and lifestyle predictors of failure using a statistical model that accounts for patient‐level clustering.
Georgios S. Chatzopoulos, Larry F. Wolff
wiley   +1 more source