Results 31 to 40 of about 4,483 (147)

Clinical profile of individuals with bisphosphonate-related osteonecrosis of the jaw: an integrative review

São Paulo Medical Journal, 2020
BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is still the most prevalent type of osteonecrosis with clinical relevance. In Brazil, bisphosphonate use is high but there is a lack of epidemiological studies on BRONJ. OBJECTIVE: To
Aloizio Premoli Maciel, Reyna Aguilar Quispe, Lázara Joyce Oliveira Martins, Rogério Jardim Caldas, Paulo Sérgio da Silva Santos   +4 more
doaj   +1 more source

Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice

Communications Medicine, 2022
Okawa et al. evaluate a fluorescent risedronate analogue, 800CW-pRIS, as a potential treatment for medication-related osteonecrosis of the jaw. The authors demonstrate an improvement in wound healing and inflammation with 800CW-pRIS pre-treatment in a ...
Hiroko Okawa, Takeru Kondo, Akishige Hokugo, Philip Cherian, Oskar Sundberg, Jesus J. Campagna, Boris A. Kashemirov, Varghese John, Shuting Sun, Frank H. Ebetino, Charles E. McKenna, Ichiro Nishimura   +11 more
doaj   +1 more source

Comparative survival analysis of endodontic re‐treatment and single‐tooth implants: A retrospective cohort study using shared frailty modeling

Journal of Prosthodontics, EarlyView.
Abstract Purpose To compare the long‐term survival of nonsurgical endodontic re‐treatment versus single‐tooth implants and to identify independent demographic, systemic, and lifestyle predictors of failure using a statistical model that accounts for patient‐level clustering.
Georgios S. Chatzopoulos, Larry F. Wolff
wiley   +1 more source

Low awareness of medication-related osteonecrosis of the jaw among dentists: a systematic review with a medical and bioethical perspective

BMC Medical Ethics
Introduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious adverse drug reaction that can seriously affect the quality of life of patients if not promptly diagnosed and treated. To date, preventive measures have been the most effective
Martina Coppini, Sonia Arduini, Rodolfo Mauceri, Isabel Ascension Trujillo Perez, Giuseppina Campisi   +4 more
doaj   +1 more source

Knowledge and Attitudes of Oral Health Professionals to Different Dental Treatment Approaches in Bisphosphonate Therapy

Current Research in Dental Sciences
Objective: This study evaluates oral healthcare professionals’ attitudes towards managing different dental clinical scenarios considering different durations and administration routes of antiresorptive drugs. Methods: This study is a cross-sectional, Web-
Şebnem Dirikan İpci, Gökser Çakar, Cavid Ahmedbeyli, İlknur Özenci, Yasemin Dedeoğlu   +4 more
doaj   +1 more source

Pathophysiology of Medication‐Related Osteonecrosis of the Jaw—A Minireview

JBMR Plus, 2023
Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse effect of antiresorptive medications administered for control of osseous malignancy, osteoporosis, or other bone metabolic diseases.
Sotirios Tetradis, Matthew R. Allen, Salvatore L. Ruggiero   +2 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

The Role Of Hmgb1-Related Inflammation Signals In Bronj

International Dental Journal
Aim or purpose: BRONJ causes prolonged inflammation, resulting in delayed wound healing. High mobility group box-1 (HMGB1) is secreted into the extracellular milieu in response to stimuli, which mediates various inflammatory diseases and affects wound ...
Li Shurong, Yan Jiayi
doaj   +1 more source

Bisphosphonates and Their Influence on the Implant Failure: A Systematic Review

Applied Sciences, 2023
Objective: The goal of this systematic review was to study the relationship between the use of bisphosphonates (oral or intravenous) and its effect on implant osseointegration. Methods: The focused question was “In patients medicated with bisphosphonates
Cristiana Gomes Rebelo, Juliana Campos Hasse Fernandes, Nuno Bernardo, Patrícia Couto, Gustavo Vicentis Oliveira Fernandes   +4 more
doaj   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source