Results 31 to 40 of about 381,165 (242)
Essential Medicinal Chemistry of Essential Medicines [PDF]
Journal of Medicinal Chemistry, 2020 Since 1977, the World Health Organization publishes a list of essential medicines, i.e., those that satisfy the priority health care needs of the population and are selected with regard to disease prevalence and public health relevance, evidence of clinical efficacy, and safety, as well as comparative costs and cost-effectiveness.
Marta Serafini +4 more
openaire +3 more sources
Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
, 2016 The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA +4 more
core +1 more source
Spotlight on medicinal chemistry education [PDF]
, 2014 Open access articleThe field of medicinal chemistry is constantly evolving and it is important for medicinal chemists to develop the skills and knowledge required to succeed and contribute to the advancement of the field. Future Medicinal Chemistry spoke
Pitman, Simone +3 more
core +2 more sources
The Importance of Medicinal Chemistry Knowledge in the Clinical Pharmacist's Education [PDF]
, 2018 Objective. To show why medicinal chemistry must be a key component of the education of pharmacy students, as well as in the pharmacist's practice. Findings.
Fernandes, Joao Paulo S.
core +2 more sources
Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models [PDF]
Current Medicinal Chemistry, 2018, 2021 In the present review, we describe three hot topics in cancer research such as circulating tumor cells, exosomes, and 3D environment models. The first section is dedicated to microfluidic platforms for detecting circulating tumor cells, including both affinity based methods that take advantage of antibodies and aptamers, and label free approaches ...
arxiv +1 more source
Development of Advanced Macrosphelides: Potent Anticancer Agents
Molecules, 2015 Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography ...
Seung-Mann Paek
doaj +1 more source
Metal Complexes and Medicine: A Successful Combination
CHIMIA, 2015 Since the start of our independent research at the Department of Chemistry of the University of Zurich in 2009, our group has been, among other topics, working on the use of metal complexes in medicinal chemistry.
Gilles Gasser
doaj +1 more source
arXiv, 2023 Nobel laureates cluster together. 696 of the 727 winners of the Nobel Prize in physics, chemistry, medicine, and economics belong to one single academic family tree. 668 trace their ancestry to Emmanuel Stupanus, 228 to Lord Rayleigh (physics, 1904). Craig Mello (medicine, 2006) counts 51 Nobelists among his ancestors. Chemistry laureates have the most
arxiv
On the Virtues of Automated QSAR The New Kid on the Block [PDF]
Future Medicinal Chemistry, 2017, 2017 Quantitative Structure-Activity Relationship (QSAR) has proved an invaluable tool in medicinal chemistry. Data availability at unprecedented levels through various databases have collaborated to a resurgence in the interest for QSAR. In this context, rapid generation of quality predictive models is highly desirable for hit identification and lead ...
arxiv +1 more source