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The Association Between Medroxyprogesterone Acetate Exposure and Cerebral Meningioma Among a Medicaid Population [PDF]

open access: goldEpidemiologia
Background/Objectives: Medroxyprogesterone acetate (MPA) is a synthetic contraceptive that can be used orally or as a once-every-three-month injection (i.e., depot MPA [dMPA]).
Lindy M. Reynolds   +2 more
doaj   +4 more sources

Effects of Donepezil and Medroxyprogesterone Versus Placebo on Weaning in Adult Patients With Non-Pulmonary Etiologies Receiving Invasive Mechanical Ventilation: A triple‐blind Randomized Clinical Trial [PDF]

open access: goldFrontiers in Pharmacology, 2021
Background: Medroxyprogesterone and donepezil could be used as respiratory stimulants in ventilated patients. However, no randomized placebo-controlled trial is available to confirm this approach and compare these drugs.
Zahra Alizadeh   +4 more
doaj   +2 more sources

Case Report: Development of persistent genital arousal disorder due to a possible combination of medications [PDF]

open access: yesFrontiers in Psychiatry
ObjectivePersistent Genital Arousal Disorder (PGAD) is a rare and distressing condition characterized by persistent genital arousal in the absence of sexual desire.
Ludek Fiala   +3 more
doaj   +2 more sources

Self-administered subcutaneous medroxyprogesterone acetate for improving contraceptive outcomes: a systematic review and meta-analysis [PDF]

open access: goldBMC Women's Health, 2021
Background Subcutaneous depot medroxyprogesterone acetate is an easy-to-use injectable contraceptive. A trained person can administer it, including women through self-injection.
Ashraf Nabhan   +4 more
doaj   +2 more sources

A Matched Case-Control Study Examining the Association Between Exposure to Depot Medroxyprogesterone Acetate and Cerebral Meningioma Using an Active Comparator [PDF]

open access: yesCurrent Oncology
The recent literature has reported an increased association between the use of depot medroxyprogesterone acetate (dMPA) and cerebral meningioma (CM). Prior studies have been limited in generalizability and did not use an active comparator as a control ...
Russell Griffin, Rebecca Arend
doaj   +2 more sources

Live Birth Outcomes After Extended or Repeated High-Dose Medroxyprogesterone Acetate Therapy for Fertility-Sparing Management of Endometrial Neoplasia: A Single-Center Retrospective Case Series. [PDF]

open access: yesJ Obstet Gynaecol Res
ABSTRACT Aim To clarify live birth outcomes among women receiving extended or repeated high‐dose medroxyprogesterone acetate (MPA) therapy for fertility‐sparing management of atypical endometrial hyperplasia or endometrioid carcinoma grade 1. Methods We conducted a single‐center retrospective case series of 53 patients undergoing MPA therapy between ...
Yamamura A   +9 more
europepmc   +2 more sources

Medroxyprogesterone promotes neuronal survival after cerebral ischemic stroke by inhibiting PARthanatos [PDF]

open access: yesFrontiers in Pharmacology
IntroductionCerebral ischemic stroke (CIS) is caused by the interruption of cerebral blood circulation due to thrombosis or embolism and is the second-leading cause of mortality worldwide.
Chang-Ling Yue   +12 more
doaj   +2 more sources

Combined high dose vitamin C and E increases oxidative stress and visceral fat mass in rats treated by depot-medroxyprogesterone acetate

open access: diamondMiddle East Fertility Society Journal, 2016
Objective: This study was aimed to investigate the effect of combined vitamin C and E on serum leptin, visceral fat mass, and visceral fat oxidative stress in rats treated by depot-medroxyprogesterone acetate (DMPA).
Endang Sri Wahyuni   +2 more
doaj   +2 more sources

Prognostic Biomarker of Fertility-Preserving Hormonal Therapy Based on Multigene Panel Testing for Endometrial Cancer. [PDF]

open access: yesCancer Sci
We identified prognostic biomarkers that predict treatment outcomes in patients receiving fertility‐preserving high‐dose medroxyprogesterone acetate (MPA) therapy through comprehensive multigene panel testing. ABSTRACT In this study, we identified prognostic biomarkers that predict treatment outcome in patients receiving fertility‐preserving high‐dose ...
Hirano T   +10 more
europepmc   +2 more sources

Uterine leiomyoma and its association with menstrual pattern and history of depo-medroxyprogesterone acetate injections

open access: goldInternational Journal of General Medicine, 2011
L Amanti2, H Sadeghi-Bazargani1, H Abdollahi2, F Ehdaeivand31Statistics and Epidemiology Department, Faculty of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran; 2Tabriz University of Medical Sciences, Tabriz, Iran; 3Faculty of ...
Amanati L   +4 more
doaj   +3 more sources

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