Results 1 to 10 of about 13,223 (143)

Case Report: Development of persistent genital arousal disorder due to a possible combination of medications [PDF]

Frontiers in Psychiatry
ObjectivePersistent Genital Arousal Disorder (PGAD) is a rare and distressing condition characterized by persistent genital arousal in the absence of sexual desire.
Ludek Fiala, Ludek Fiala, Jiří Lenz, Jiří Lenz   +3 more
doaj   +2 more sources

A Matched Case-Control Study Examining the Association Between Exposure to Depot Medroxyprogesterone Acetate and Cerebral Meningioma Using an Active Comparator [PDF]

Current Oncology
The recent literature has reported an increased association between the use of depot medroxyprogesterone acetate (dMPA) and cerebral meningioma (CM). Prior studies have been limited in generalizability and did not use an active comparator as a control ...
Russell Griffin, Rebecca Arend
doaj   +2 more sources

Medroxyprogesterone promotes neuronal survival after cerebral ischemic stroke by inhibiting PARthanatos [PDF]

Frontiers in Pharmacology
IntroductionCerebral ischemic stroke (CIS) is caused by the interruption of cerebral blood circulation due to thrombosis or embolism and is the second-leading cause of mortality worldwide.
Chang-Ling Yue, Chang-Ling Yue, Yan-Xia Ding, Meng Chen, Meng Chen, Yu-Xin Shen, Ao-Meng Hu, Hai Huang, Zhao-Huan Zhang, Ying-Xin Zhou, Ying-Xin Zhou, Xiao-Hui Xu, Xiao-Hui Xu   +12 more
doaj   +2 more sources

The Association Between Medroxyprogesterone Acetate Exposure and Cerebral Meningioma Among a Medicaid Population [PDF]

Epidemiologia
Background/Objectives: Medroxyprogesterone acetate (MPA) is a synthetic contraceptive that can be used orally or as a once-every-three-month injection (i.e., depot MPA [dMPA]).
Lindy M. Reynolds, Rebecca Arend, Russell L. Griffin   +2 more
doaj   +2 more sources

The value of diffusion-weighted imaging and semi-quantitative dynamic contrast-enhanced MRI in predicting the efficacy of medroxyprogesterone acetate treatment for atypical endometrial hyperplasia and endometrial carcinoma [PDF]

BMC Medical Imaging
Background It will be important to noninvasively evaluate the efficacy of treatment for patients with atypical endometrial hyperplasia (AEH) and endometrial carcinoma (EC) who wish to have children. The study aimed to explore the feasibility of diffusion-
Mingming Liu, Xingzheng Zheng, Na Mo, Yang Liu, Erhu Jin, Yuting Liang   +5 more
doaj   +2 more sources

Effects of Donepezil and Medroxyprogesterone Versus Placebo on Weaning in Adult Patients With Non-Pulmonary Etiologies Receiving Invasive Mechanical Ventilation: A triple‐blind Randomized Clinical Trial

Frontiers in Pharmacology, 2021
Background: Medroxyprogesterone and donepezil could be used as respiratory stimulants in ventilated patients. However, no randomized placebo-controlled trial is available to confirm this approach and compare these drugs.
Zahra Alizadeh, Adeleh Sahebnasagh, Navid Hadadzadegan, Farhad Mohammadi, Fatemeh Saghafi   +4 more
doaj   +1 more source

Comparison of Dydrogesterone and Medroxyprogesterone in the Progestin-Primed Ovarian Stimulation Protocol for Patients With Poor Ovarian Response

Frontiers in Endocrinology, 2021
ObjectiveTo compare the clinical outcomes of dydrogesterone (DYG) and medroxyprogesterone (MPA) in the progestin-primed ovarian stimulation (PPOS) protocol for patients with poor ovarian response (POR).Patients and MethodsThis was a retrospective cohort ...
Junwei Zhang, Mingze Du, Zhen Li, Wenxia Liu, Bingnan Ren, Yuchao Zhang, Yichun Guan   +6 more
doaj   +1 more source

Medroxyprogesterone acetate improves propionic acid-induced autism rat model and magnetic resonance spectroscopic correlation

Bangladesh Journal of Pharmacology, 2022
The protective effect of medroxyprogesterone acetate on propionic acid-induced autism in rats was evaluated. For this purpose, 30 rats were divided into three groups.
Mehmet Fatih Bozkurt, Muhammad Nasir Bhaya, İbrahim Halil Sever, Bahattin Özkul, Oytun Erbaş   +4 more
doaj   +1 more source

Progestogens Are Metabolized by the Gut Microbiota: Implications for Colonic Drug Delivery

Pharmaceutics, 2020
Following oral administration, the bioavailability of progestogens is very low and highly variable, in part due to metabolism by cytochrome P450 enzymes found in the mucosa of the small intestine.
Zoe Coombes, Vipul Yadav, Laura E. McCoubrey, Cristina Freire, Abdul W. Basit, R. Steven Conlan, Deyarina Gonzalez   +6 more
doaj   +1 more source

Evaluation of the Safety and Efficacy of Ormeloxifene, a Selective Estrogen Receptor Modulator and Medroxyprogesterone Acetate in Women with Non-Structural Abnormal Uterine Bleeding: A Randomized Clinical Trial

Medicina, 2022
Background and objectives: Abnormal uterine bleeding is a significant clinical and gynaecological concern that necessitates its safe and effective treatment.
Suhail Ahmad Mir, Rifat Ara, Fiza Amin, Anjum Malik, Laraibah Hamid, Tabasum Ali, Ghulam Nabi Bader, Shahid Ud Din Wani, Mansour Almuqbil, Sultan Alshehri, Abdulhakeem M. Alshehri, Faiyaz Shakeel   +11 more
doaj   +1 more source